“Morningside’s investment in Synchroneuron demonstrates our belief in the potential of SNC-102 to safely and effectively treat neuropsychiatric disorders such as tardive dyskinesia as well as its potential in additional indications,” said
Top-line data from Synchroneuron’s Phase 2, multi-center, randomized, double-blind, placebo-controlled trial of SNC-102 is expected early in 2015. Approximately half of the subjects have entered or already completed the study. In addition, Synchroneuron expects to begin open label studies of SNC-102 in Tourette syndrome and post-traumatic stress syndrome (PTSD) to prove the concept of the drug’s broader efficacy for neuropsychiatric disorders potentially related to glutamate/GABA imbalance.
“SNC-102 has the potential to be the first
Funds from the Series B will support the Company’s active formulation improvement program, additional open label studies of SNC-102 and preclinical studies to better understand acamprosate’s pharmacokinetics and mechanism of action through the end of 2016.
Morningside, founded in 1986, is a diversified investment company with portfolio investments in private equity and technology ventures. The group invests actively in biotech companies founded on novel science. For more information, visit www.morningside.com.
About Tardive Dyskinesia
Tardive dyskinesia (TD) is a chronic movement disorder caused by prolonged exposure to medications that block dopamine receptors, including antipsychotic drugs and some drugs used to treat nausea. It is characterized by involuntary, repetitive movements that usually involve the face and in more severe cases affect the trunk and/or extremities. Involuntary movements of the lips, cheeks, tongue and jaw are typical. The disorder is irreversible in the majority of cases. TD may affect as many as one million people in the U.S. alone and 200,000 or more with moderate to severe symptoms. TD has been recognized for nearly six decades but to date there is no generally-accepted or
SNC-102 is a unique formulation of acamprosate calcium, an
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