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Study Data from Technical University Provide New Insights into Biosensing (Noise Limits of CMOS Current Interfaces for Biosensors: A Review)

July 9, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Biosensing. According to news reporting from Milan, Italy, by NewsRx journalists, research stated, "Current sensing readout is one of the most frequent techniques used in biosensing due to the charge-transfer phenomena occurring at solid-liquid interfaces. The development of novel nanodevices for biosensing determines new challenges for electronic interface design based on current sensing, especially when compact and efficient arrays need to be organized, such as in recent trends of rapid label-free electronic detection of DNA synthesis."

The news correspondents obtained a quote from the research from Technical University, "This paper will review the basic noise limitations of current sensing interfaces with particular emphasis on integrated CMOS technology. Starting from the basic theory, the paper presents, investigates and compares charge-sensitive amplifier architectures used in both continuous-time and discrete-time approaches, along with their design trade-offs involving noise floor, sensitivity to stray capacitance and bandwidth. The ultimate goal of this review is providing analog designers with helpful design rules and analytical tools."

According to the news reporters, the research concluded: "Also, in order to present a comprehensive overview of the state-of-the-art, the most relevant papers recently appeared in the literature about this topic are discussed and compared."

For more information on this research see: Noise Limits of CMOS Current Interfaces for Biosensors: A Review. IEEE Transactions on Biomedical Circuits and Systems, 2014;8(2):278-292. IEEE Transactions on Biomedical Circuits and Systems can be contacted at: Ieee-Inst Electrical Electronics Engineers Inc, 445 Hoes Lane, Piscataway, NJ 08855-4141, USA. (Institute of Electrical and Electronics Engineers -; IEEE Transactions on Biomedical Circuits and Systems -

Our news journalists report that additional information may be obtained by contacting M. Crescentini, Politecn Milan, Dipartimento Elettron Informaz & Bioingn, I-20133 Milan, Italy. Additional authors for this research include M. Bennati, M. Carminati and M. Tartagni (see also Biosensing).

Keywords for this news article include: Milan, Italy, Europe, Biosensing, Bioengineering, Bionanotechnology, Nanobiotechnology

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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