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Studies in the Area of Oligopeptides Reported from Razi University (Indirect colorimetric detection of glutathione based on its radical restoration...

July 8, 2014



Studies in the Area of Oligopeptides Reported from Razi University (Indirect colorimetric detection of glutathione based on its radical restoration ability using carbon nanodots as nanozymes)

By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Peptides is the subject of a report. According to news reporting from Kermanshah, Iran, by NewsRx journalists, research stated, "This work addresses a colorimetric sensor for glutathione (GSH). In this study carbon nanodots (CDs) were used as the peroxidase mimetic catalysts."

The news correspondents obtained a quote from the research from Razi University, "The blue colored free cation radicals were generated simply by an oxidation reaction of tetramethyl benzidine (TMB) which was catalyzed by CDs as the catalysts. So, the key role of the CDs was the enhancement in radical generation thereby enhancing the system sensitivity. The results in this study showed that the free radical cation concentration was inversely related to the GSH concentration in the range of 0-7 mu M with a detection limit of 0.3 mu M. Moreover, this system showed a perfect selectivity over non-thiolated biological molecules."

According to the news reporters, the research concluded: "As a practical application, this chemosensor was used to measure the GSH content of the whole human blood with the results consistent with that of a classical Ellman method."

For more information on this research see: Indirect colorimetric detection of glutathione based on its radical restoration ability using carbon nanodots as nanozymes. Sensors and Actuators B-Chemical, 2014;199():463-469. Sensors and Actuators B-Chemical can be contacted at: Elsevier Science Sa, PO Box 564, 1001 Lausanne, Switzerland (see also Peptides).

Our news journalists report that additional information may be obtained by contacting M. Shamsipur, Razi Univ, Fac Sci, Dept. of Chem, Kermanshah, Iran. Additional authors for this research include A. Safavi and Z. Mohammadpour.

Keywords for this news article include: Iran, Asia, Nanodot, Kermanshah, Glutathione, Oligopeptides, Nanotechnology, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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