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Researchers' Work from Dankook University Focuses on Clinical Trials and Studies (Dynamic cell culture on porous biopolymer microcarriers in a...

July 9, 2014



Researchers' Work from Dankook University Focuses on Clinical Trials and Studies (Dynamic cell culture on porous biopolymer microcarriers in a spinner flask for bone tissue engineering: a feasibility study)

By a News Reporter-Staff News Editor at Biotech Week -- Data detailed on Clinical Research have been presented. According to news reporting originating in Cheonan, South Korea, by NewsRx journalists, research stated, "Porous microspherical carriers have great promise for cell culture and tissue engineering. Dynamic cultures enable more uniform cell population and effective differentiation than static cultures."

The news reporters obtained a quote from the research from Dankook University, "Here we applied dynamic spinner flask culture for the loading and multiplication of cells onto porous biopolymer microcarriers. The abilities of the microcarriers to populate cells and to induce osteogenic differentiation were examined and the feasibility of in vivo delivery of the constructs was addressed. Over time, the porous microcarriers enabled cell adhesion and expansion under proper dynamic culture conditions. Osteogenic markers were substantially expressed by the dynamic cell cultures. The cell-cultured microcarriers implanted in the mouse subcutaneous tissue for 4 weeks showed excellent tissue compatibility, with minimal inflammatory signs and significant induction of bone tissues."

According to the news reporters, the research concluded: "This first report on dynamic culture of porous biopolymer microcarriers providing an effective tool for bone tissue engineering."

For more information on this research see: Dynamic cell culture on porous biopolymer microcarriers in a spinner flask for bone tissue engineering: a feasibility study. Biotechnology Letters, 2014;36(7):1539-1548. Biotechnology Letters can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Biotechnology Letters - www.springerlink.com/content/0141-5492/)

Our news correspondents report that additional information may be obtained by contacting G.Z. Jin, Dankook University, Sch Dental, Dept. of Biomat Sci, Cheonan 330714, South Korea. Additional authors for this research include J.H. Park, S.J. Seo and H.W. Kim (see also Clinical Research).

Keywords for this news article include: Asia, Tissue Engineering, Biomedical Engineering, Biomedicine, Cheonan, South Korea, Bone Research, Bioengineering, Clinical Research, Clinical Trials and Studies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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