Researchers from Royal London Hospital Discuss Findings in Knee Replacement (Single-stage revision for the infected total knee replacement RESULTS FROM A SINGLE CENTRE)
By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Knee Replacement. According to news reporting originating from London, United Kingdom, by NewsRx correspondents, research stated, "Peri-prosthetic infection is amongst the most common causes of failure following total knee replacement (TKR). In the presence of established infection, thorough joint debridement and removal of all components is necessary following which new components may be implanted."
Our news editors obtained a quote from the research from Royal London Hospital, "This can be performed in one or two stages; two-stage revision with placement of an interim antibiotic-loaded spacer is regarded by many to be the standard procedure for eradication of peri-prosthetic joint infection. We present our experience of a consecutive series of 50 single-stage revision TKRs for established deep infection performed between 1979 and 2010. There were 33 women and 17 men with a mean age at revision of 66.8 years (42 to 84) and a mean follow-up of 10.5 years (2 to 24). The mean time between the primary TKR and the revision procedure was 2.05 years (1 to 8). Only one patient required a further revision for recurrent infection, representing a success rate of 98%. Nine patients required further revision for aseptic loosening, according to microbiological testing of biopsies taken at the subsequent surgery. Three other patients developed a further septic episode but none required another revision. These results suggest that a single-stage revision can produce comparable results to a two-stage revision."
According to the news editors, the research concluded: "Single-stage revision offers a reduction in costs as well as less morbidity and inconvenience for patients."
For more information on this research see: Single-stage revision for the infected total knee replacement RESULTS FROM A SINGLE CENTRE. Bone & Joint Journal, 2014;96B(6):759-764. Bone & Joint Journal can be contacted at: British Editorial Soc Bone Joint Surgery, 22 Buckingham Street, London WC2N 6ET, England (see also Knee Replacement).
The news editors report that additional information may be obtained by contacting S. Tibrewal, Barts Hlth NHS Trust, Royal London Hospital, London, United Kingdom. Additional authors for this research include F. Malagelada, L. Jeyaseelan, F. Posch and G. Scott.
Keywords for this news article include: Biomedical Engineering, Biomedicine, London, Europe, United Kingdom, Bioengineering, Medical Devices, Knee Replacement
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