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Researchers from Institute of Medicine Report New Studies and Findings in the Area of Biotechnology (Long-term stability in biomass and production of...

July 9, 2014



Researchers from Institute of Medicine Report New Studies and Findings in the Area of Biotechnology (Long-term stability in biomass and production of terpene indole alkaloids by hairy root culture of Rauvolfia serpentina and cost approximation ...)

By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Technology. According to news reporting from Uttar Pradesh, India, by NewsRx journalists, research stated, "The effect of 6 years of cultivation and use of table-sugar (TS) on the biomass/terpene alkaloid productivities and rol gene expression were studied in a hairy root (HR) clone of Rauvolfia serpentina. The media cost could be reduced > 94 % by replacing sucrose (SUC) with TS-an unexplored avenue for HR cultivation."

The news correspondents obtained a quote from the research from the Institute of Medicine, "The overall productivities increased over long-term cultivation with sugar proving superior to SUC for biomass (24.4 +/- A 2.11 g/l DW after 40 days to 17.31 % higher) and reserpine (0.094 +/- A 0.008 % DW after 60 days to 193.8 % more) production. The latter however revealed comparatively better yields concerning ajmaline (0.507 +/- A 0.048 % DW after 60 days to 61.98 % higher) and yohimbine (0.628 +/- A 0.062 % DW after 60 days to 38.32 % higher), respectively."

According to the news reporters, the research concluded: "PCR amplification of rol genes confirmed long-term expression stability."

For more information on this research see: Long-term stability in biomass and production of terpene indole alkaloids by hairy root culture of Rauvolfia serpentina and cost approximation to endorse commercial realism. Biotechnology Letters, 2014;36(7):1523-1528. Biotechnology Letters can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Biotechnology Letters - www.springerlink.com/content/0141-5492/)

Our news journalists report that additional information may be obtained by contacting P. Pandey, Cent Inst Med & Aromat Plants CSIR CIMAP, Div Med Chem, Lucknow 226015, Uttar Pradesh, India. Additional authors for this research include R. Kaur, S. Singh, S.K. Chattopadhyay, S.K. Srivastava and S. Banerjee (see also Technology).

Keywords for this news article include: Asia, India, Technology, Uttar Pradesh

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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