Researchers at University of Washington Report Findings in Molecular Imaging (Magnetomotive photoacoustic imaging: in vitro studies of magnetic trapping with simultaneous photoacoustic detection of rare circulating tumor cells)
By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Molecular Imaging. According to news reporting out of Seattle, Washington, by NewsRx editors, research stated, "Photoacoustic (PA) imaging has been demonstrated to be a promising modality in molecular imaging for detection of nanoparticle-targeted diseased cells or tissues. However, intrinsic absorbers, such as blood, produce strong PA background signals that severely degrade the detection sensitivity and specificity of targeted objects."
Our news journalists obtained a quote from the research from the University of Washington, "Magnetomotive photoacoustic (mmPA) imaging, a newly developed molecular imaging modality, introduced dynamic manipulation into traditional PA imaging. Unlike conventional PA imaging, magnetomotive manipulation with simultaneous ultrasound/PA imaging of agents incorporating magnetic nanoparticles enables direct visualization of the signal generating object and can dramatically reduce background signals from strong optical absorbers. This paper briefly reviews recent developments in mmPA imaging, including uses of composite contrast agent, design of magnet system, and data processing for motion filtering."
According to the news editors, the research concluded: "The use of mmPA imaging in detecting rare circulating tumor cells in blood vessels, which remains a big challenge for real-time in vivo examination using current methodologies, was also addressed."
For more information on this research see: Magnetomotive photoacoustic imaging: in vitro studies of magnetic trapping with simultaneous photoacoustic detection of rare circulating tumor cells. Journal of Biophotonics, 2013;6(6-7):513-22. (Wiley-Blackwell - www.wiley.com/; Journal of Biophotonics - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1864-0648)
Our news journalists report that additional information may be obtained by contacting C.W. Wei, Dept. of Bioengineering, University of Washington, Seattle, WA 98195, United States. Additional authors for this research include J. Xia, I. Pelivanov, C. Jia, S.W. Huang, X. Hu, X. Gao and M. O'Donnell (see also Molecular Imaging).
Keywords for this news article include: Seattle, Washington, United States, Nanotechnology, Molecular Imaging, Emerging Technologies, North and Central America.
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