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Reports Outline DNA Vaccines Study Findings from E.L. Brown and Colleagues (Treatment of Metastatic Equine Melanoma with a Plasmid DNA Vaccine...

July 8, 2014



Reports Outline DNA Vaccines Study Findings from E.L. Brown and Colleagues (Treatment of Metastatic Equine Melanoma with a Plasmid DNA Vaccine Encoding Streptococcus Pyogenes EMM55 Protein)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Biotechnology have been published. According to news reporting out of Tampa, Florida, by NewsRx editors, research stated, "A 19-year-old castrated male Arab/Quarter horse presented with an extensive history of cutaneous metastatic melanoma. Over a period of 8 months, a total of 8 doses of plasmid DNA vaccine expressing the Streptococcus pyogenes emm55 gene (pAc/emm55) were administered intratumorally at 300 mu g/dose via a needless injector."

Our news journalists obtained a quote from the research, "Upon completion of the vaccination protocol, the size of the injected lesions, on average, were reduced by 40.3% from the initial size measurements. Lesions that were not injected were reduced by 47.6%. The overall reduction in total tumor burden was 42.3%."

According to the news editors, the research concluded: "Tumor regression was also associated with the augmentation of antimelanoma IgG antibody response, thus implying that an induction of an effective antimelanoma response would be of great advantage in the management of equine melanoma."

For more information on this research see: Treatment of Metastatic Equine Melanoma with a Plasmid DNA Vaccine Encoding Streptococcus Pyogenes EMM55 Protein. Journal of Equine Veterinary Science, 2014;34(5):704-708. Journal of Equine Veterinary Science can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Journal of Equine Veterinary Science - www.elsevier.com/wps/product/cws_home/636592)

Our news journalists report that additional information may be obtained by contacting E.L. Brown, Moiphogenesis Inc, Tampa, FL 33614, United States. Additional authors for this research include V.K. Ramiya, C.A. Wright, M.M. Jerald, A.D. Via, V.N. Kuppala, W.S. Hazell, P.D. Lawman and M.J. Lawman (see also Biotechnology).

Keywords for this news article include: Biotechnology, Tampa, Florida, DNA Vaccines, United States, Streptococcaceae, Synthetic Vaccines, Gram-Positive Bacteria, Streptococcus pyogenes, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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