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Reports Outline DNA Research Study Results from Jilin University [Fluorescence detection of Pb(2+) based on the DNA sequence functionalized CdS...

July 9, 2014



Reports Outline DNA Research Study Results from Jilin University [Fluorescence detection of Pb(2+) based on the DNA sequence functionalized CdS quantum dots]

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on DNA Research have been published. According to news reporting out of Changchun, People's Republic of China, by NewsRx editors, research stated, "In this paper, we have developed a simple and rapid method for the detection of Pb(2+) based on the DNA sequence capped CdS quantum dots (QDs). We utilized the designed guanine (G)-rich DNA sequence (PS2.M) as a coating reagent to synthesize the DNA-capped CdS QDs."

Our news journalists obtained a quote from the research from Jilin University, "The designed G-rich DNA sequence PS2.M can bind with hemin to form G-quadruplex/hemin complex with K(+), accompanied by the fluorescence quenching of CdS QDs via the photoinduced electron transfer. Pb(2+) can induce conformational changes in the G-quadruplex/hemin complex to release the hemin molecules, so the quenched fluorescence of CdS QDs could be recovered."

According to the news editors, the research concluded: "Therefore, the new fluorescent analysis system could be applied for the detection of Pb(2+) based on the label-free DNA sequence capped CdS QDs."

For more information on this research see: Fluorescence detection of Pb(2+) based on the DNA sequence functionalized CdS quantum dots. Biosensors & Bioelectronics, 2014;58():17-21. (Elsevier - www.elsevier.com; Biosensors & Bioelectronics - www.elsevier.com/wps/product/cws_home/405913)

Our news journalists report that additional information may be obtained by contacting S. Liu, Dept. of Analytical Chemistry, College of Chemistry, Jilin University, Changchun 130012, People's Republic of China. Additional authors for this research include W. Na, S. Pang and X. Su (see also DNA Research).

Keywords for this news article include: Asia, Heme, Drugs, Hemin, Therapy, Changchun, Porphyrins, DNA Research, Quantum Dots, Quantum Physics, Biological Factors, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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