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Recent Findings in Aldehydes Described by Researchers from East China University of Science and Technology (Immobilization of penicillin G acylase on...

July 8, 2014



Recent Findings in Aldehydes Described by Researchers from East China University of Science and Technology (Immobilization of penicillin G acylase on paramagnetic aldehyde-functionalized mesostructured cellular foams)

By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Aldehydes are presented in a new report. According to news reporting out of Shanghai, People's Republic of China, by NewsRx editors, research stated, "Paramagnetic aldehyde-functionalized mesostructured cellular foams (PAMCFs), synthesized by grafting 3-aminopropyltriethoxysilane modified Fe3O4 (NH2-Fe3O4) nanoparticles with larger particle size than the window pore size of MCFs on the outer surface of aldehyde-functionalized mesostructured cellular foams (AMCFs), were investigated as efficient supports for immobilization of penicillin G acylase (PGA)."

Our news journalists obtained a quote from the research from the East China University of Science and Technology, "The results show that NH2-Fe3O4 nanoparticles were successfully grafted on the outer surface of AMCFs and PGA molecules were mainly immobilized covalently on the inner surface of PAMCFs, which was because amino groups of NH2-Fe3O4 nanoparticles or PGA molecules reacted with aldehyde groups of AMCFs or PAMCFs to form imine bonds. PGA/PAMCFs-15 showed a rather high initial activity of 9563 U g(-1) and retained 89.1% of its initial activity after recycled for 10 times."

According to the news editors, the research concluded: "PGA/PAMCFs are easily recycled by magnetic field in order to replace tedious separation of high-speed centrifugation for mesoporous materials."

For more information on this research see: Immobilization of penicillin G acylase on paramagnetic aldehyde-functionalized mesostructured cellular foams. Enzyme and Microbial Technology, 2014;60():32-39. Enzyme and Microbial Technology can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Enzyme and Microbial Technology - www.elsevier.com/wps/product/cws_home/525004)

Our news journalists report that additional information may be obtained by contacting L. Yang, E. China University of Science & Technology, Res Inst Ind Catalysis, Key Lab Adv Mat, Shanghai 200237, People's Republic of China. Additional authors for this research include Z.Y. Gao, Y.L. Guo, W.C. Zhan, Y. Guo, Y.S. Wang and G.Z. Lu (see also Aldehydes).

Keywords for this news article include: Asia, Shanghai, Aldehydes, Penicillins, Nanoparticle, beta-Lactams, Nanotechnology, Organic Chemicals, Emerging Technologies, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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