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New Microscopy and Microanalysis Study Findings Reported from M.J. Dukes and Co-Authors (Improved microchip design and application for in situ...

July 8, 2014



New Microscopy and Microanalysis Study Findings Reported from M.J. Dukes and Co-Authors (Improved microchip design and application for in situ transmission electron microscopy of macromolecules)

By a News Reporter-Staff News Editor at Journal of Technology -- A new study on Microscopy and Microanalysis is now available. According to news reporting out of Raleigh, North Carolina, by VerticalNews editors, research stated, "Understanding the fundamental properties of macromolecules has enhanced the development of emerging technologies used to improve biomedical research. Currently, there is a critical need for innovative platforms that can illuminate the function of biomedical reagents in a native environment."

Our news journalists obtained a quote from the research, "To address this need, we have developed an in situ approach to visualize the dynamic behavior of biomedically relevant macromolecules at the nanoscale. Newly designed silicon nitride devices containing integrated 'microwells' were used to enclose active macromolecular specimens in liquid for transmission electron microscopy imaging purposes.We were able to successfully examine novel magnetic resonance imaging contrast reagents, micelle suspensions, liposome carrier vehicles, and transcribing viral assemblies."

According to the news editors, the research concluded: "With each specimen tested, the integrated microwells adequately maintained macromolecules in discrete local environments while enabling thin liquid layers to be produced."

For more information on this research see: Improved microchip design and application for in situ transmission electron microscopy of macromolecules. Microscopy and Microanalysis, 2014;20(2):338-45. (Cambridge University Press - www.cambridge.org; Microscopy and Microanalysis - journals.cambridge.org/action/displayJournal?jid=MAM)

Our news journalists report that additional information may be obtained by contacting M.J. Dukes, 1 Protochips Inc, Raleigh, NC 27606, United States. Additional authors for this research include R. Thomas, J. Damiano, K.L. Klein, S. Balasubramaniam, S. Kayandan, J.S. Riffle, R.M. Davis, S.M. McDonald and D.F Kelly.

Keywords for this news article include: Raleigh, United States, North Carolina, North and Central America, Microscopy and Microanalysis.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Journal of Technology


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