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New Immunoglobulins Study Results Reported from UPMC [Investigating the Kinetics of Antibody Adsorption onto Polyethylene Terephthalate (PET)...

July 8, 2014



New Immunoglobulins Study Results Reported from UPMC [Investigating the Kinetics of Antibody Adsorption onto Polyethylene Terephthalate (PET) Modified with Gold Nanoparticles in Flow Microchannel]

By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Immunology is the subject of a report. According to news reporting originating from Paris, France, by NewsRx correspondents, research stated, "The real-time monitoring of the adsorption kinetic of antibody onto polyethylene terephthalate (PET) modified with gold nanoparticles (NPs) is performed into a dielectric flow microchannel. The principle is based on the microelectrode- dielectric interface excitation by a modulated voltage excitation through the dielectric layer with high frequency range."

Our news editors obtained a quote from the research from UPMC, "The set-up configuration using a homemade current-to-voltage converter has been developed for fast monitoring of biomolecule adsorption without direct electrical contact of microelectrodes with the microchannel flow. The change in the interfacial admittance, related to the output voltage measured through the microchip, during antibody incubation, gives information on the kinetics involved while antibodies are adsorbed at the interface. An example of adsorption on PET modified with gold NPS was taken."

According to the news editors, the research concluded: "Experimental data were fit with the Langmuir equation and a good correlation was obtained with this latter, where the equilibrium constant, K, was found as 1.55 x 10(8) M-1 with a limit of detection for antibody concentration without depletion equal to 8.25 nM."

For more information on this research see: Investigating the Kinetics of Antibody Adsorption onto Polyethylene Terephthalate (PET) Modified with Gold Nanoparticles in Flow Microchannel. Journal of Flow Chemistry, 2014;4(2):66-71. Journal of Flow Chemistry can be contacted at: Akademiai Kiado Rt, Prielle K U 19, PO Box 245, H-1117 Budapest, Hungary (see also Immunology).

The news editors report that additional information may be obtained by contacting M. Kechadi, UPMC, Lab Physiol Cellulaire & Mol Plantes, UR 5, F-75005 Paris, France. Additional authors for this research include M. Faure, B. Sotta and J. Gamby.

Keywords for this news article include: Antibodies, Paris, France, Europe, Alkenes, Polyenes, Immunology, Hydrocarbons, Nanoparticle, Polyethylenes, Blood Proteins, Nanotechnology, Immunoglobulins, Organic Chemicals, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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