News Column

New Immunoglobulins Data Have Been Reported by Researchers at Ehime University (A microfluidic device containing membrane-immobilized antibodies for...

July 8, 2014



New Immunoglobulins Data Have Been Reported by Researchers at Ehime University (A microfluidic device containing membrane-immobilized antibodies for successively capturing cytosolic enzymes)

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Immunology. According to news reporting originating in Matsuyama, Japan, by NewsRx journalists, research stated, "A microfluidic device containing membrane-immobilized anti-esterase (ES) antibodies and anti-lactate dehydrogenase (LDH) antibodies was prepared. The membrane was prepared by transferring antibodies that had been separated by non-denaturing two-dimensional electrophoresis to a polyvinylidene difluoride membrane, which was then stained and cut into small pieces (16 mm(2))."

The news reporters obtained a quote from the research from Ehime University, "In this microfluidic device, > 0.014 Unit mL(-1) of the purified porcine carboxylesterase was specifically captured by membrane-immobilized anti- ES antibodies and > 147 Unit mL(-1) of purified porcine LDH was specifically captured by membrane-immobilized anti-LDH antibodies. Furthermore, ES and LDH in micro-scale aliquots of porcine liver cytosol were successively captured by membrane-immobilized antibodies in the device, and the enzyme activities were quantitatively analyzed by spectrofluorometry."

According to the news reporters, the research concluded: "The results indicate that the microfluidic device containing membrane-immobilized antibodies can be used to investigate the activities of several types of intact enzymes."

For more information on this research see: A microfluidic device containing membrane-immobilized antibodies for successively capturing cytosolic enzymes. Talanta, 2014;125():400-404. Talanta can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Talanta - www.elsevier.com/wps/product/cws_home/525438)

Our news correspondents report that additional information may be obtained by contacting Y. Shimazaki, Ehime University, Fac Sci, Matsuyama, Ehime 790, Japan (see also Immunology).

Keywords for this news article include: Asia, Japan, Matsuyama, Immunology, Blood Proteins, Immunoglobulins, Serum Globulins, Immobilized Proteins, Enzymes and Coenzymes, Immobilized Antibodies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


For more stories covering the world of technology, please see HispanicBusiness' Tech Channel



Source: Life Science Weekly


Story Tools






HispanicBusiness.com Facebook Linkedin Twitter RSS Feed Email Alerts & Newsletters