News Column

New Findings from Center for Environmental Health in the Area of Nanoparticles Described (The application of QSAR approaches to nanoparticles)

July 8, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Nanoparticles. According to news reporting originating from Neuherberg, Germany, by NewsRx correspondents, research stated, "Nanoparticles (NPs) are increasingly used throughout the world for many purposes. The resulting exposure increases the relevance of efforts to assess their effects."

Our news editors obtained a quote from the research from Center for Environmental Health, "The activities of NPs are related to many structural features, including their shape, composition and size. Applying Quantitative Structure-Activity Relationship (QSAR) methods to nanoscale systems becomes challenging, due to the lack of data and insight into the fate and effects of NPs. In this study, the possible use of QSAR methods on NPs is investigated. To this intent, several ways of representing and describing NPs were tested by using different data mining methods. The main conclusion is that QSAR methods are relevant for the study of the activity of NPs, but this should be confirmed by using larger and more diverse sets of data. Moreover, representing the constitution of NPs (in terms of core, coating and surface modification) significantly increases the prediction accuracy of the models."

According to the news editors, the research concluded: "In our case, the most significant features to be represented were found to be the core and surface modification."

For more information on this research see: The application of QSAR approaches to nanoparticles. Alternatives To Laboratory Animals, 2014;42(1):43-50. Alternatives To Laboratory Animals can be contacted at: Frame, Russell & Burch House 96-98 North Sherwood St, Nottingham NG1 4EE, Notts, England (see also Nanoparticles).

The news editors report that additional information may be obtained by contacting J. Ehret, Helmholtz-Zentrum Munchen - German Research Centre for Environmental Health (GmbH), Institute of Molecular Exposomics, Neuherberg, Munich, Germany. Additional authors for this research include M. Vijver and W. Peijnenburg.

Publisher contact information for the journal Alternatives To Laboratory Animals is: Frame, Russell & Burch House 96-98 North Sherwood St, Nottingham NG1 4EE, Notts, England.

Keywords for this news article include: Europe, Germany, Neuherberg, Nanotechnology, Emerging Technologies.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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