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New Excitatory Amino Acids Findings from Osaka University Described [Preparation of siRNA Carrier Based on Boronic Acid-functionalized Amphiphilic...

July 8, 2014



New Excitatory Amino Acids Findings from Osaka University Described [Preparation of siRNA Carrier Based on Boronic Acid-functionalized Amphiphilic Poly(gamma-glutamic acid) Nanoparticles]

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Excitatory Amino Acids have been published. According to news originating from Osaka, Japan, by NewsRx correspondents, research stated, "Boronic acid-grafted amphiplailic poly(gamma-glutamic acid) was (a) successfully synthesized with carbodiimide."

Our news journalists obtained a quote from the research from Osaka University, "These copolymers could form 200-nn-sized monodispersed nanoparticles (NPs). These NPs were stable in saline and could efficiently load small interfering RNA (siRNA) in a dose-dependent manner at about 80% efficiency."

According to the news editors, the research concluded: "These results demonstrated that the polymer chemistry could contribute to the development of siRNA-based gene therapies."

For more information on this research see: Preparation of siRNA Carrier Based on Boronic Acid-functionalized Amphiphilic Poly(gamma-glutamic acid) Nanoparticles. Chemistry Letters, 2014;43(6):840-842. Chemistry Letters can be contacted at: Chemical Soc Japan, 1-5 Kanda-Surugadai Chiyoda-Ku, Tokyo, 101-8307, Japan (see also Excitatory Amino Acids).

The news correspondents report that additional information may be obtained from F. Shima, Osaka University, Grad Sch Engn, Dept. of Appl Chem, Suita, Osaka 5650871, Japan. Additional authors for this research include M. Shudo, T. Akagi and M. Akashi.

Keywords for this news article include: Asia, Osaka, Japan, Nanoparticle, Boronic Acids, Glutamic Acid, Nanotechnology, Boron Compounds, Acidic Amino Acids, Noncarboxylic Acids, Emerging Technologies, Excitatory Amino Acids, Dicarboxylic Amino Acids

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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