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Investigators from Tsinghua University Have Reported New Data on Cardiology (Engineering Three-Dimensional Cardiac Microtissues for Potential Drug...

July 9, 2014

Investigators from Tsinghua University Have Reported New Data on Cardiology (Engineering Three-Dimensional Cardiac Microtissues for Potential Drug Screening Applications)

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Cardiology. According to news reporting from Beijing, People's Republic of China, by NewsRx journalists, research stated, "Heart disease is one of the major global health issues. Despite rapid advances in cardiac tissue engineering, limited successful strategies have been achieved to cure cardiovascular diseases."

The news correspondents obtained a quote from the research from Tsinghua University, "This situation is mainly due to poor understanding of the mechanism of diverse heart diseases and unavailability of effective in vitro heart tissue models for cardiovascular drug screening. With the development of microengineering technologies, three-dimensional (3D) cardiac microtissue (CMT) models, mimicking 3D architectural microenvironment of native heart tissues, have been developed. The engineered 3D CMT models hold greater potential to be used for assessing effective drugs candidates than traditional two-dimensional cardiomyocyte culture models."

According to the news reporters, the research concluded: "This review discusses the development of 3D CMT models and highlights their potential applications for high-throughput screening of cardiovascular drug candidates."

For more information on this research see: Engineering Three-Dimensional Cardiac Microtissues for Potential Drug Screening Applications. Current Medicinal Chemistry, 2014;21(22):2497-2509. Current Medicinal Chemistry can be contacted at: Bentham Science Publ Ltd, Executive Ste Y-2, PO Box 7917, Saif Zone, 1200 Br Sharjah, U Arab Emirates. (Bentham Science Publishers -; Current Medicinal Chemistry -

Our news journalists report that additional information may be obtained by contacting L. Wang, Tsinghua Univ, Sch Med, Dept. of Biomed Engn, Beijing 100084, People's Republic of China. Additional authors for this research include G. Huang, B. Sha, S. Wang, Y.L. Han, J. Wu, Y. Li, Y. Du, T.J. Lu and F. Xu (see also Cardiology).

Keywords for this news article include: Asia, Tissue Engineering, Beijing, Cardiology, Cardiovascular, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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