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Investigators from Tabriz University of Medical Sciences Zero in on Virology (A sight on the current nanoparticle-based gene delivery vectors)

July 8, 2014

By a News Reporter-Staff News Editor at Virus Weekly -- Investigators publish new report on Virology. According to news reporting originating from Tabriz, Iran, by NewsRx correspondents, research stated, "Nowadays, gene delivery for therapeutic objects is considered one of the most promising strategies to cure both the genetic and acquired diseases of human. The design of efficient gene delivery vectors possessing the high transfection efficiencies and low cytotoxicity is considered the major challenge for delivering a target gene to specific tissues or cells."

Our news editors obtained a quote from the research from the Tabriz University of Medical Sciences, "On this base, the investigations on non-viral gene vectors with the ability to overcome physiological barriers are increasing. Among the non-viral vectors, nanoparticles showed remarkable properties regarding gene delivery such as the ability to target the specific tissue or cells, protect target gene against nuclease degradation, improve DNA stability, and increase the transformation efficiency or safety. This review attempts to represent a current nanoparticle based on its lipid, polymer, hybrid, and inorganic properties."

According to the news editors, the research concluded: "Among them, hybrids, as efficient vectors, are utilized in gene delivery in terms of materials (synthetic or natural), design, and in vitro/in vivo transformation efficiency."

For more information on this research see: A sight on the current nanoparticle-based gene delivery vectors. Nanoscale Research Letters, 2014;9():1-9. Nanoscale Research Letters can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer -; Nanoscale Research Letters -

The news editors report that additional information may be obtained by contacting S.M. Dizaj, Tabriz Univ Med Sci, Dept. of Pharmacognosy, Fac Pharm, Tabriz 14766, Iran. Additional authors for this research include S. Jafari and A.Y. Khosroushahi (see also Virology).

Keywords for this news article include: Iran, Asia, Tabriz, Virology

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Source: Virus Weekly

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