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Findings on Bioinformatics Detailed by Investigators at Washington University (Supercomputing for the parallelization of whole genome analysis)

July 8, 2014

By a News Reporter-Staff News Editor at Information Technology Newsweekly -- Research findings on Bioinformatics are discussed in a new report. According to news reporting originating from St. Louis, Missouri, by VerticalNews correspondents, research stated, "The declining cost of generating DNA sequence is promoting an increase in whole genome sequencing, especially as applied to the human genome. Whole genome analysis requires the alignment and comparison of raw sequence data, and results in a computational bottleneck because of limited ability to analyze multiple genomes simultaneously."

Our news editors obtained a quote from the research from Washington University, "We now adapted a Cray XE6 supercomputer to achieve the parallelization required for concurrent multiple genome analysis. This approach not only markedly speeds computational time but also results in increased usable sequence per genome."

According to the news editors, the research concluded: "Relying on publically available software, the Cray XE6 has the capacity to align and call variants on 240 whole genomes in similar to 50 h. Multisample variant calling is also accelerated."

For more information on this research see: Supercomputing for the parallelization of whole genome analysis. Bioinformatics, 2014;30(11):1508-1513. Bioinformatics can be contacted at: Oxford Univ Press, Great Clarendon St, Oxford OX2 6DP, England. (Oxford University Press -; Bioinformatics -

The news editors report that additional information may be obtained by contacting M.J. Puckelwartz, Washington University, Sch Med, St Louis, MO 63110, United States. Additional authors for this research include L.L. Pesce, V. Nelakuditi, L. Dellefave-Castillo, J.R. Golbus, S.M. Day, T.P. Cappola, G.W. Dorn, I.T. Foster and E.M. McNally.

Keywords for this news article include: Missouri, St. Louis, United States, Bioinformatics, North and Central America

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Source: Information Technology Newsweekly

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