Findings from Kangwon National University Provide New Insights into Nanoparticles (Multiple detection of proteins by SERS-based immunoassay with core shell magnetic gold nanoparticles)
By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Nanoparticles. According to news reporting originating in Chunchon, South Korea, by NewsRx journalists, research stated, "A highly selective and sensitive surface-enhanced Raman scattering (SERS)-based immunoassay for the multiple detection of proteins has been developed. The proposed core shell magnetic gold (Au) nanopartides allow for successful protein separation and high SERS enhancement for protein detection."
The news reporters obtained a quote from the research from Kangwon National University, "To selectively detect a specific protein in a mixed protein solution, we employed the sandwich type SERS immunoassay with core shell magnetic Au nanoparticles utilizing specific antigen-antibody interactions. Based on this proposed SERS immunoassay, we can successfully detect proteins in very low concentrations (similar to 800 ag/mL of mouse lgG and similar to 5 fg/mL of human IgG) with high reproducibility. Magnetically assisted protein separation and detection by this proposed SERS immunoassay would provide great potential for effective and sensitive multiple protein detection."
According to the news reporters, the research concluded: "This technique allows for the straightforward SERS-based bioassays for quantitative protein detections."
For more information on this research see: Multiple detection of proteins by SERS-based immunoassay with core shell magnetic gold nanoparticles. Vibrational Spectroscopy, 2014;72():44-49. Vibrational Spectroscopy can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Vibrational Spectroscopy - www.elsevier.com/wps/product/cws_home/504273)
Our news correspondents report that additional information may be obtained by contacting M.H. Shin, Kangwon Natl Univ, Dept. of Biol Sci, Chunchon 200701, South Korea. Additional authors for this research include W. Hong, Y. Sa, L. Chen, Y.J. Jung, X. Wang, B. Zhao and Y.M. Jung (see also Nanoparticles).
Keywords for this news article include: Asia, Chunchon, South Korea, Nanotechnology, Gold Nanoparticles, Emerging Technologies
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