News Column

Data on Bioinformatics Discussed by Researchers at University of Illinois (ARTS: automated randomization of multiple traits for study design)

July 8, 2014

By a News Reporter-Staff News Editor at Information Technology Newsweekly -- Research findings on Bioinformatics are discussed in a new report. According to news reporting originating from Lemont, Illinois, by VerticalNews correspondents, research stated, "Collecting data from large studies on high-throughput platforms, such as microarray or next-generation sequencing, typically requires processing samples in batches."

Our news editors obtained a quote from the research from the University of Illinois, "There are often systematic but unpredictable biases from batch-to-batch, so proper randomization of biologically relevant traits across batches is crucial for distinguishing true biological differences from experimental artifacts. When a large number of traits are biologically relevant, as is common for clinical studies of patients with varying sex, age, genotype and medical background, proper randomization can be extremely difficult to prepare by hand, especially because traits may affect biological inferences, such as differential expression, in a combinatorial manner."

According to the news editors, the research concluded: "Here we present ARTS (automated randomization of multiple traits for study design), which aids researchers in study design by automatically optimizing batch assignment for any number of samples, any number of traits and any batch size."

For more information on this research see: ARTS: automated randomization of multiple traits for study design. Bioinformatics, 2014;30(11):1637-1639. Bioinformatics can be contacted at: Oxford Univ Press, Great Clarendon St, Oxford OX2 6DP, England. (Oxford University Press -; Bioinformatics -

The news editors report that additional information may be obtained by contacting M. Maienschein-Cline, University of Illinois, Argonne Natl Lab, Lemont, IL, United States. Additional authors for this research include Z.D. Lei, V. Gardeux, T. Abbasi, R.F. Machado, V. Gordeuk, A.A. Desai, S. Saraf, N. Bahroos and Y. Lussier.

Keywords for this news article include: Lemont, Illinois, United States, Bioinformatics, North and Central America

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Source: Information Technology Newsweekly

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