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Researchers from Tsinghua University Discuss Findings in Hazardous Materials (Antiestrogenic activity and related disinfection by-product formation...

July 22, 2014



Researchers from Tsinghua University Discuss Findings in Hazardous Materials (Antiestrogenic activity and related disinfection by-product formation induced by bromide during chlorine disinfection of sewage secondary effluent)

By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Hazardous Materials have been presented. According to news reporting from Shenzhen, People's Republic of China, by NewsRx journalists, research stated, "Chlorine disinfection, widely used in wastewater reclamation, can form toxic and harmful disinfection by-products (DBPs), some of which are associated with endocrine disruption. In this study, the presence of bromide was found to promote an increase in antiestrogenic activity using a yeast two-hybrid assay in the sewage secondary effluent during chlorine disinfection."

The news correspondents obtained a quote from the research from Tsinghua University, "Among the dissolved organic matters in the secondary effluent, hydrophobic acids and hydrophilic substance fractions were determined as potential precursors associated with increase in antiestrogenic activity in the secondary effluent induced by bromide. Further antiestrogenic activity evaluation and mass spectrum characterization following the semipreparative liquid chromatography fractionation of a natural organic matter precursor, tyrosine, after chlorination under the presence of bromide revealed, for the first time, that 2-(bromo-4-hydroxyphenyl) acetonitrile (Br-HPAN) and 2-(dibromo-4-hydroxyphenyl) acetonitrile (DBr-HPAN) exhibited antiestrogenic activity. Br-HPAN and DBr-HPAN were the DBPs involved in the increase in antiestrogenic activity in the tyrosine solution."

According to the news reporters, the research concluded: "Bromide was shown to induce the formation of Br-HPAN and DBr-HPAN in the secondary effluent during chlorine disinfection."

For more information on this research see: Antiestrogenic activity and related disinfection by-product formation induced by bromide during chlorine disinfection of sewage secondary effluent. Journal of Hazardous Materials, 2014;273():280-6. (Elsevier - www.elsevier.com; Journal of Hazardous Materials - www.elsevier.com/wps/product/cws_home/502691)

Our news journalists report that additional information may be obtained by contacting Q.Y. Wu, Shenzhen Laboratory of Microorganism Application and Risk Control, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, People's Republic of China. Additional authors for this research include X. Tang, H. Huang, Y. Li, H.Y. Hu, Y.N. Ding and Y.R Shao (see also Hazardous Materials).

Keywords for this news article include: Asia, Shenzhen, Hazardous Materials, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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