News Column

Reports Outline Hemorrhage Findings from Stanford University (Miniature Electrical Stimulator for Hemorrhage Control)

July 23, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Hemorrhage. According to news reporting from Stanford, California, by NewsRx journalists, research stated, "Noncompressible hemorrhage is currently the most common cause of preventable death in battlefield and in civilian trauma injuries. Tourniquets, specialized wound dressings, and hemorrhage-inhibiting biomaterials are not sufficiently effective in arrest of noncompressible hemorrhage and often cause collateral tissue damage."

The news correspondents obtained a quote from the research from Stanford University, "An effective, easy-to-use, portable device is needed to reduce blood loss in trauma patients immediately following injury and to maintain hemorrhage control up to several hours-until the injured is evacuated to a medical facility. We developed a miniature electrical stimulator to induce vascular constriction and, thereby, reduce hemorrhage. Vasoconstriction of the rat femoral arteries and veins was studied with pulse durations in the range of 1 mu s to 10 ms and repetition rate of 10 Hz. Pulse amplitude of 20 V, duration of 1 ms, and repetition rate of 10 Hz were found sufficient to induce rapid constriction down to 31 +/- 2% of the initial diameter, which could be maintained throughout a two-hour treatment. Within one minute following treatment termination the artery dilated back to 88 +/- 3% of the initial diameter, providing rapid restoration of blood perfusion. Histology indicated no damage to the vessel wall and endothelium seven days after stimulation. The same treatment reduced the blood loss following complete femoral artery resection by 68 +/- 11%, compared to untreated vessels."

According to the news reporters, the research concluded: "Very low power consumption during stimulation (

For more information on this research see: Miniature Electrical Stimulator for Hemorrhage Control. IEEE Transactions on Biomedical Engineering, 2014;61(6):1765-1771. IEEE Transactions on Biomedical Engineering can be contacted at: Ieee-Inst Electrical Electronics Engineers Inc, 445 Hoes Lane, Piscataway, NJ 08855-4141, USA. (Institute of Electrical and Electronics Engineers -; IEEE Transactions on Biomedical Engineering -

Our news journalists report that additional information may be obtained by contacting M.R. Brinton, Stanford University, Hansen Expt Phys Lab, Stanford, CA 94305, United States. Additional authors for this research include Y. Mandel, R. Dalal and D. Palanker (see also Hemorrhage).

Keywords for this news article include: Stanford, California, Hemorrhage, United States, North and Central America

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Source: Biotech Week

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