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Recent Findings from University of Crete Has Provided New Data on Drug Testing and Analysis [Rapid method for the simultaneous determination of DDTs...

July 25, 2014



Recent Findings from University of Crete Has Provided New Data on Drug Testing and Analysis [Rapid method for the simultaneous determination of DDTs and PCBs in hair of children by headspace solid phase microextraction and gas ...]

By a News Reporter-Staff News Editor at Drug Week -- Current study results on Drugs and Therapies have been published. According to news reporting originating from Crete, Greece, by NewsRx correspondents, research stated, "The purpose of this study was to develop a rapid and cost efficient hair extraction method, using the headspace solid phase microextraction (HSSPME) technique for the simultaneous determination and biomonitoring of 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane) (DDT) and its isomers/metabolites and polychlorinated biphenyls (PCBs) in hair samples. A total of 72 head hair samples were collected from children living in urban and rural regions of the island of Crete."

Our news editors obtained a quote from the research from the University of Crete, "Two hundred milligrams of hair were digested under alkaline conditions and thermostated for 30?min at 90C while a 65?m PDMS/DVB fibre was exposed into the headspace of the vial. Analytical parameters of the method (time of incubation, agitation speed, recovery, precision, accuracy, carry over, matrix effect, linearity, and selectivity) were examined. Recoveries of the DDTs in the spiked hair samples were calculated from 42.3% for opDDD to 87.1% for opDDE, while recoveries for PCB congeners were from 52.6% for PCB138 to 96.6 % for PCB28. The method was applied for the analysis of authentic hair samples. Significant differences (p=0.001) of the burden to total DDTs (sumDDTs) as well as of the frequencies of detection of positive samples (p=0.020) were observed between the examined regions. Moreover, significant differences in the detected concentrations of PCB congeners were observed for PCB52 (p

According to the news editors, the research concluded: "HSSPME was found to be substantially simpler and faster procedure than previous reported sample treatment procedures."

For more information on this research see: Rapid method for the simultaneous determination of DDTs and PCBs in hair of children by headspace solid phase microextraction and gas chromatography-mass spectrometry (HSSPME/GC-MS). Drug Testing and Analysis, 2014;6 Suppl 1():85-92. (Wiley-Blackwell - www.wiley.com/; Drug Testing and Analysis - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1942-7611)

The news editors report that additional information may be obtained by contacting M.N. Tzatzarakis, Center of Toxicology Science and Research, Medical School, University of Crete, Heraklion, Crete, Greece. Additional authors for this research include E.G. Barbounis, M.P. Kavvalakis, E. Vakonaki, E. Renieri, A.I. Vardavas and A.M Tsatsakis (see also Drugs and Therapies).

Keywords for this news article include: Crete, Greece, Europe, Drugs and Therapies.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Drug Week


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