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Recent Findings by J. Malaczewska and Colleagues in Immune System Provides New Insights (Effect of 28-day oral administration of silver nanocolloid...

July 25, 2014



Recent Findings by J. Malaczewska and Colleagues in Immune System Provides New Insights (Effect of 28-day oral administration of silver nanocolloid on the peripheral blood leukocytes in mice)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Immunology have been published. According to news reporting originating from Olsztyn, Poland, by NewsRx editors, the research stated, "Silver nanoparticles, which have found a wide range of applications owing to their antimicrobial properties, are also recommended as dietary supplements in alternative medicine. Studies on rodents confirm that nanosilver is absorbed from the digestive tract into the bloodstream, which implies its possible interactions with leukocytes."

Our news editors obtained a quote from the research, "The objective of the experiment discussed herein has been to determine the effect of 28-day oral administration of different doses (0.25, 2.5, 25 ppm) of commercial silver nanocolloid on hematological parameters, percentages of particular lymphocyte populations and activity of the peripheral blood leukocytes in mice. All the tested colloid doses decreased the counts of monocytes in the animals' blood and induced phenotypic modifications among lymphocytes: an increase in CD4+/CD8+ T cell distribution, a decrease in NK and NKT cell distribution (doses of 0.25 and 2.5 ppm) and an increased CD4+:CD8+ ratio (25 ppm). Silver nanocolloid also affected the activity of cells, depressing the proliferation of lymphocytes (0.25 ppm) and stimulating phagocytosis as well as the respiratory burst of granulocytes and monocytes (all doses)."

According to the news editors, the research concluded: "The results verify the influence of orally administered silver colloid on the peripheral blood leukocytes, at the same time implying the potential risk of developing an inappropriate immune response of an organism exposed to prolonged administration of this substance."

For more information on this research see: Effect of 28-day oral administration of silver nanocolloid on the peripheral blood leukocytes in mice. Polish Journal of Veterinary Sciences, 2014;17(2):263-273. Polish Journal of Veterinary Sciences can be contacted at: Polish Acad Sciences, Committee Veterinary Sciences, Univ Warmia & Mazury, Dept Animal Anatomy, Ul Oczapowskiego 14, Bldg 105J, Olsztyn-Kortowo Ii, 10957, Poland (see also Immunology).

The news editors report that additional information may be obtained by contacting J. Malaczewska, University of Warmia & Mazury, Fac Vet Med, Dept. of Microbiol & Clin Immunol, PL-10718 Olsztyn, Poland.

Keywords for this news article include: Poland, Europe, Olsztyn, Monocytes, Immunology, Blood Cells, Lymphocytes, Mononuclear Leukocytes, Hemic and Immune Systems, Mononuclear Phagocyte System

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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