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New Findings from University of Paris in Drug Delivery Systems Provides New Insights (Nanoprecipitation and the "Ouzo effect"Application to drug...

July 23, 2014



New Findings from University of Paris in Drug Delivery Systems Provides New Insights (Nanoprecipitation and the "Ouzo effect"Application to drug delivery devices)

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Drugs and Therapies have been published. According to news reporting originating in Orsay, France, by NewsRx journalists, research stated, "Biodegradable nanocarriers such as lipid- or polymer-based nanoparticles can be designed to improve the efficacy and reduce the toxic side effects of drugs. Under appropriate conditions, nanoprecipitation of a hydrophobic compound solution in a non-solvent can generate a dispersion of nanoparticles with a narrow distribution of sizes without the use of surfactant ('Ouzo' effect)."

The news reporters obtained a quote from the research from the University of Paris, "The aim of this review is to present the main parameters controlling the nucleation and growth of aggregates in a supersaturated solution and the characteristics of the obtained nanoparticles. The importance of the kinetics of mixing of the solution containing the hydrophobic compound and the non-solvent is highlighted."

According to the news reporters, the research concluded: "Illustrative examples of polymeric nanoparticles for drug delivery or terpenoid-based nanoprodrugs obtained by nanoprecipitation are reported."

For more information on this research see: Nanoprecipitation and the "Ouzo effect"Application to drug delivery devices. Advanced Drug Delivery Reviews, 2014;71():86-97. Advanced Drug Delivery Reviews can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Advanced Drug Delivery Reviews - www.elsevier.com/wps/product/cws_home/505508)

Our news correspondents report that additional information may be obtained by contacting E. Lepeltier, University of Paris, Inst Galien Paris Sud, UMR CNRS 8612, Orsay, France. Additional authors for this research include C. Bourgaux and P. Couvreur (see also Drugs and Therapies).

Keywords for this news article include: Orsay, France, Europe, Nanoparticle, Nanotechnology, Drugs and Therapies, Drug Delivery Systems, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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