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New Findings from College of Chemistry and Life Science Describe Advances in Molecular Biology (Systematic investigation of interactions between...

July 22, 2014



New Findings from College of Chemistry and Life Science Describe Advances in Molecular Biology (Systematic investigation of interactions between papain and MPA-capped CdTe quantum dots)

By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Life Science Research are presented in a new report. According to news reporting originating from Nanning, People's Republic of China, by NewsRx correspondents, research stated, "Fluorescent quantum dots (QDs) have been widely applied in biological and biomedical areas, but relatively little is known about the interaction of QDs with some natural enzymes. Herein, the interactions between 3-mercaptopropionic acid-capped CdTe QDs (MPA-QDs) and papain were systematically investigated by UV-Vis absorption spectra, fluorescence spectra and circular dichroism (CD) spectra under the physiological conditions."

Our news editors obtained a quote from the research from the College of Chemistry and Life Science, "The fluorescence spectra results indicated that MPA-QDs quenched the fluorescence intensity of papain. The modified Stern-Volmer quenching constant K a at different temperatures and the corresponding thermodynamic parameters ?H, ?G and ?S were also calculated. The binding of MPA-QDs and papain is a result of the formation of QDs-papain complex and the electrostatic interactions play a major role in stabilizing the complex."

According to the news editors, the research concluded: "The CD technique was further used to analyze the conformational changes of papain induced by MPA-QDs and the results indicated that the biological activity of papain was affected by MPA-QDs dramatically."

For more information on this research see: Systematic investigation of interactions between papain and MPA-capped CdTe quantum dots. Molecular Biology Reports, 2013;40(10):5781-9. Molecular Biology Reports can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Springer - www.springer.com; Molecular Biology Reports - www.springerlink.com/content/0301-4851/)

The news editors report that additional information may be obtained by contacting Q. Xiao, College of Chemistry and Life Science, Guangxi Teachers Education University, Nanning, 530001, People's Republic of China. Additional authors for this research include H. Qiu, S. Huang, C. Huang, W. Su, B. Hu and Y. Liu (see also Life Science Research).

Publisher contact information for the journal Molecular Biology Reports is: Springer, 233 Spring Street, New York, NY 10013, USA.

Keywords for this news article include: Asia, Nanning, Quantum Dots, Quantum Physics, Life Science Research, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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