Investigators at Chinese Academy of Sciences Report Findings in Enzymes and Coenzymes (Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of ...)
By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on Enzymes and Coenzymes is now available. According to news reporting originating from Beijing, People's Republic of China, by NewsRx correspondents, research stated, "Artificial enzyme mimics are a current research interest, and many nanomaterials have been found to display enzyme-mimicking activity. However, to the best of our knowledge, there have not hitherto been any reports on the use of pure nanomaterials to construct a system capable of mimicking an enzyme cascade reaction."
Our news editors obtained a quote from the research from the Chinese Academy of Sciences, "Herein, we describe the construction of a novel nanocomposite consisting of V2O5 nanowires and gold nanoparticles (AuNPs) through a simple and facile chemical method, in which V2O5 and AuNPs possess intrinsic peroxidase and glucose oxidase (GOx)-like activity, respectively. Results suggest that this material can mimic the enzyme cascade reaction of horseradish peroxidase (HRP) and GOx. Based on this mechanism, a direct and selective colorimetric method for the detection of glucose has been successfully designed. Because single-strand and double-strand DNA (ssDNA and dsDNA) have different deactivating effects on the GOx-like activity of AuNPs, the sensing of target complementary DNA can also be realized and disease-associated single-nucleotide polymorphism of DNA can be easily distinguished."
According to the news editors, the research concluded: "Our study opens a new avenue for the use of nanomaterials in enzyme mimetics, and holds promise for the further exploration of nanomaterials in creating alternative catalytic systems to natural enzymes."
For more information on this research see: Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of Biomolecules. Chemistry-A European Journal, 2014;20(24):7501-7506. Chemistry-A European Journal can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany (see also Enzymes and Coenzymes).
The news editors report that additional information may be obtained by contacting K.G. Qu, Univ Chinese Academy Sci, Beijing 100039, People's Republic of China. Additional authors for this research include P. Shi, J.S. Ren and X.G. Qu.
Keywords for this news article include: Asia, Beijing, Nanowire, Peroxidases, Nanomaterial, Nanoparticle, Nanotechnology, Emerging Technologies, Enzymes and Coenzymes, People's Republic of China
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