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Findings from Xinxiang Medical University in the Area of Essential Amino Acids Reported (Selective binding and magnetic separation of...

July 22, 2014



Findings from Xinxiang Medical University in the Area of Essential Amino Acids Reported (Selective binding and magnetic separation of histidine-tagged proteins using Ni2+-decorated Fe3O4/hydroxyapatite composite nanoparticles)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Essential Amino Acids have been published. According to news originating from Xinxiang, People's Republic of China, by NewsRx correspondents, research stated, "Fe3O4/hydroxyapatite (Fe3O4/HAP) nanoparticles (NPs) were synthesized by hydrothermal method. The obtained NPs have excellent magnetic responsibility and can immobilize metal ions."

Our news journalists obtained a quote from the research from Xinxiang Medical University, "After chelating Ni2+ ions, Fe3O4/HAP-Ni2+ NPs can be used to enrich histidine-tagged (His-tagged) proteins directly from the mixture of lysed cells. Fe3O4/HAP-Ni2+ NPs present negligible nonspecific protein adsorption and high protein binding activity with the saturation capacity being 12.98 mmol/g. Their separation capcity towards His-tagged proteins was remained after 4 times recycling."

According to the news editors, the research concluded: "They are especially suitable for rapid purification of His-tagged proteins. ."

For more information on this research see: Selective binding and magnetic separation of histidine-tagged proteins using Ni2+-decorated Fe3O4/hydroxyapatite composite nanoparticles. Materials Letters, 2014;126():97-100. Materials Letters can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Materials Letters - www.elsevier.com/wps/product/cws_home/505672)

The news correspondents report that additional information may be obtained from S.S. Yao, Xinxiang Med Univ, Coll Pharm, Xinxiang 453003, People's Republic of China. Additional authors for this research include X.Q. Yan, Y.B. Zhao, B.J. Li and L. Sun (see also Essential Amino Acids).

Keywords for this news article include: Asia, Xinxiang, Histidine, Phosphates, Nanoparticle, Nanotechnology, Hydroxyapatites, Phosphoric Acids, Cyclic Amino Acids, Emerging Technologies, Essential Amino Acids, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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