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Findings from Huazhong University of Science and Technology Broaden Understanding of Chemiluminescence (A Simple, Selective and Sensitive Immunoassay...

July 25, 2014



Findings from Huazhong University of Science and Technology Broaden Understanding of Chemiluminescence (A Simple, Selective and Sensitive Immunoassay for Determination of Human Chorionic Gonadotrophin Based on Chemiluminescence Resonance Energy ...)

By a News Reporter-Staff News Editor at Health & Medicine Week -- A new study on Chemiluminescence is now available. According to news reporting originating in Hubei, People's Republic of China, by NewsRx journalists, research stated, "A simple, selective and sensitive immunoassay was developed for the determination of human chorionic gonadotrophin (HCG) based on the chemiluminescence resonance energy transfer (CRET). Two kinds of antibodies were used to form a sandwich-type immunocomplex to ensure the selectivity of immunoassay."

The news reporters obtained a quote from the research from the Huazhong University of Science and Technology, "Based on the simple magnetic separation, amplification feature of gold nanoparticles and CRET phenomenon, this method could be used for highly sensitive determination of HCG without tedious washing steps. Under the optimized conditions, a linear range was obtained when the concentrations of HCG were changed from 0.15 to 5 mIUmL(-1) (R = 0.992)."

According to the news reporters, the research concluded: "This immunoassay could be used for the determination of HCG in serum samples, which provided a promising potential in clinical diagnosis."

For more information on this research see: A Simple, Selective and Sensitive Immunoassay for Determination of Human Chorionic Gonadotrophin Based on Chemiluminescence Resonance Energy Transfer. Journal of the Chinese Chemical Society, 2014;61(6):638-642. Journal of the Chinese Chemical Society can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell - www.wiley.com/; Journal of the Chinese Chemical Society - onlinelibrary.wiley.com/journal/10.1002/(ISSN)2192-6549)

Our news correspondents report that additional information may be obtained by contacting J.Q. Lei, Huazhong University of Science & Technology, Key Lab Environm & Hlth WuhanTongji Med College, State Key Lab Environm Hlth IncubatMinist Enviro, Key Lab Environm & HlthMinist EducSch Public Hlth, Wuhan 430030, Hubei, People's Republic of China. Additional authors for this research include S.R. Mei, Y.K. Zhou and T. Jing (see also Chemiluminescence).

Keywords for this news article include: Asia, Hubei, Chemiluminescence, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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