Data on Drug Development Detailed by Researchers at Institute for Solid State Physics (Composite of Functional Mesoporous Silica and DNA: An Enzyme-Responsive Controlled Release Drug Carrier System)
By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Drug Development. According to news reporting out of Hefei, People's Republic of China, by NewsRx editors, research stated, "An efficient enzyme-responsive controlled release carrier system was successfully fabricated using single-stranded DNA encapsulated functional mesoporous silica nanoparticles."
Our news journalists obtained a quote from the research from Institute for Solid State Physics, "Mesoporous silica nanoparticles were initially fabricated through hydrolysis of tetraethyl orthosilicate (TEOS) in cetyltrimethylammonium chloride (CTAC) solution, and the surface of nanoparticles could be encapsulated with single-stranded DNA. This nanomaterial has excellent bioactivity and its hydrolysate cannot cause damage to normal cell, thus the biocompatibility of the nanomaterial is improved."
According to the news editors, the research concluded: "In addition, this nanomaterial showed an excellent drug release performance when loaded with drugs, which would be helpful to increase the treatment efficiency and decrease side effects of drugs."
For more information on this research see: Composite of Functional Mesoporous Silica and DNA: An Enzyme-Responsive Controlled Release Drug Carrier System. ACS Applied Materials & Interfaces, 2014;6(11):8042-8047. ACS Applied Materials & Interfaces can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; ACS Applied Materials & Interfaces - www.pubs.acs.org/journal/aamick)
Our news journalists report that additional information may be obtained by contacting G.L. Zhang, Chinese Academy Sci, Inst Solid State Phys, Key Lab Mat Phys, Hefei 230031, People's Republic of China. Additional authors for this research include M.L. Yang, D.Q. Cai, K. Zheng, X. Zhang, L.F. Wu and Z.Y. Wu (see also Drug Development).
Keywords for this news article include: Asia, Hefei, Therapy, DNA Research, Nanoparticle, Nanotechnology, Drug Development, Controlled Release, Drug Delivery Systems, Emerging Technologies, Enzymes and Coenzymes, People's Republic of China
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