She added that these enzymes work in tandem with the protein kinases identified by the same team in a complementary study carried out in 2010 and if they are able to find out what proteins are essential for these parasites to develop and divide then maybe they can target those proteins and arrest them with drugs or vaccines.
Using a number of molecular cell biology and biochemical techniques, Dr Tewari and her team found that half the phosphatase genes (16) could not be 'knocked out' suggesting some of these genes could be future drug targets as their presence is critical to parasite growth.
Dr Tewari said that it was interesting to see that out of the genes that could be knocked out (14), six were found to be crucial for sexual development and hence could be drug targets for parasite transmission to and from the mosquito.
She added that the research was gathered using the mouse malaria parasite which can be directly related to the human malaria parasite, as many of the genes share a very similar homology and symptoms of the diseases are very similar.
The research was carried out in collaboration with the
The research is published in the academic journal Cell Host and Microbe.(ANI)
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