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Study Findings from University of Granada Broaden Understanding of Nitro Compounds

June 13, 2014

By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Nitro Compounds. According to news reporting out of Granada, Spain, by NewsRx editors, research stated, "A novel method consisting of cation-selective exhaustive injection and sweeping (CSEI-sweeping) as on-line preconcentration followed by a micellar electrokinetic chromatography (MEKC) separation has been developed for the determination of 5-nitroimidazoles (5-NDZ) in environmental waters. Moreover, dispersive liquid-liquid microextraction (DLLME) has been proposed for first time as sample treatment technique prior to CSEI-sweeping-MEKC."

Our news journalists obtained a quote from the research from the University of Granada, "DLLME was applied to 5 mL of sample. Dibromomethane (1156 mu L) and 2-butanol (1363 mu L) were employed as extractant and dispersive solvents, respectively. Salting-out effect was achieved by the addition of 16% (w/v) NaCl to the samples. After DLLME and organic solvent evaporation, the residue was redissolved in a low conductivity solvent (5 mM phosphoric acid with 5% of methanol) and electrokinetically injected at 9.8 kV for 632 s in a bare fused-silica capillary (57.2 cm, 50 mu m I.D.). Prior to the injection, the capillary was rinsed with 50 mM phosphate buffer pH 2.5, followed by a plug of a higher conductivity buffer (100 mM phosphate pH 2.5, 50 mbar, 264 s) and a plug of water (50 mbar, 2 s). Separation was carried out applying -30 kV at 20 degrees C in 44 mM phosphate buffer pH 2.5, containing 8% tetrahydrofuran and 123 mM sodium dodecyl sulfate. Analytical signals were monitored at 276 nm. Validation was performed in river and well waters, obtaining satisfactory results in terms of linearity, precision (% RSD generally lower than 10%) and trueness (recoveries higher than 70% in almost all cases). LODs ranged from 0.61 to 2.44 ng/mL."

According to the news editors, the research concluded: "The combination of this microextraction technique with the proposed capillary electrophoresis methodology supposes a simple, sensitive and cheap alternative for 5-NDZ analyses, in accordance with the aims of green chemistry."

For more information on this research see: Novel cation selective exhaustive injection-sweeping procedure for 5-nitroimidazole determination in waters by micellar electrokinetic chromatography using dispersive liquid-liquid microextraction. Journal of Chromatography A, 2014;1341():65-72. Journal of Chromatography A can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier -; Journal of Chromatography A -

Our news journalists report that additional information may be obtained by contacting M. Hernandez-Mesa, University of Granada, Fac Sci, Dept. of Analyt Chem, E-18071 Granada, Spain. Additional authors for this research include D. Airado-Rodriguez, C. Cruces-Blanco and A.M. Garcia-Campana (see also Nitro Compounds).

Keywords for this news article include: Spain, Europe, Anions, Granada, Phosphates, Nanotechnology, Electrokinetics, Nitro Compounds, Nitroimidazoles, Phosphoric Acids, Emerging Technologies

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Source: Science Letter

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