By a News Reporter-Staff News Editor at Science Letter -- Current study results on Essential Amino Acids have been published. According to news reporting originating in Tainan, Taiwan, by NewsRx journalists, research stated, "The preparation of alkyl chain-grafted poly(L-lysine) (PLL) vesicles with tunable molecular assembly in aqueous solution and the evaluation of their membrane permeability by drug release experiments have been investigated."
The news reporters obtained a quote from the research from National Cheng Kung University, "Upon grafting long alkyl chains, polypeptides confined in the assembled nanostructures adopted ordered conformations such as alpha-helices or beta-sheets/turns, leading to the dense packing of membranes and, consequently, the decreases in vesicular size and membrane permeability. The vesicles can also be cross-linked by genipin to form stable structures with tunable membrane permeability."
According to the news reporters, the research concluded: "Additionally, these vesicles exhibited noticeable pH-sensitive behavior, depending on the grafted alkyl chain and cross-linking."
For more information on this research see: Alkyl Chain-Grafted Poly(L-lysine) Vesicles with Tunable Molecular Assembly and Membrane Permeability. ACS Macro Letters, 2014;3(3):220-223. ACS Macro Letters can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; ACS Macro Letters - www.pubs.acs.org/journal/amlccd)
Our news correspondents report that additional information may be obtained by contacting B.Y. Chen, National Cheng Kung University, Dept. of Chem Engn, Tainan 701, Taiwan. Additional authors for this research include Y.F. Huang, Y.C. Huang, T.C. Wen and J.S. Jan (see also Essential Amino Acids).
Keywords for this news article include: Asia, Tainan, Taiwan, Lysine, Nanotechnology, Basic Amino Acids, Diamino Amino Acids, Molecular Assemblies, Emerging Technologies, Essential Amino Acids
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