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New Biochemical Engineering Study Results from Z.M. Lu et al Described (Modified arthroconidial inoculation method for the efficient fermentation of...

July 2, 2014



New Biochemical Engineering Study Results from Z.M. Lu et al Described (Modified arthroconidial inoculation method for the efficient fermentation of Antrodia camphorata ATCC 200183)

By a News Reporter-Staff News Editor at Journal of Engineering -- Current study results on Biochemical Engineering have been published. According to news reporting originating from Jiangsu, People's Republic of China, by VerticalNews correspondents, research stated, "Large-scale submerged fermentation (SmF) of Antrodia camphorata usually encounters engineering problems, such as long period and complex fermentation. In this study, a modified inoculation method using arthroconidia sporulated in liquid medium was developed for an efficient large-scale fermentation of A. camphorata ATCC 200183."

Our news editors obtained a quote from the research, "The optimum environmental and nutritional conditions for arthroconidial germination in the dark control were estimated as follows: temperature, 26 degrees C; glucose, 20 g/L; soybean peptone, 10 g/L; Mg2+ concentration, 2 mmol/L; and initial pH, 3.5. All the arthroconidia rapidly germinated within 32 h after inoculation under optimal conditions. In the shaking flask, prepared according to the arthroconidial inoculation method, the fermentation period, maximal cell growth rate, and triterpenoid productivity of SmF were 0.6-, 1.7-, and 1.6-fold of those obtained from the culture prepared according to the conventional mycelial inoculation method. Furthermore, efficient fermentation was obtained in a 4000L fermentor, with a biomass of 7.84 +/- 0.20 g/L and a triterpenoid production of 61.21 +/- 2.12 mg/L."

According to the news editors, the research concluded: "Therefore, the modified inoculation method can be used in engineering applications with several advantages, including simplicity, good controllability, and high efficiency (shorten the operation time of mycelium-based inoculation from >= 240 h to 168 h)."

For more information on this research see: Modified arthroconidial inoculation method for the efficient fermentation of Antrodia camphorata ATCC 200183. Biochemical Engineering Journal, 2014;87():41-49. Biochemical Engineering Journal can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Biochemical Engineering Journal - www.elsevier.com/wps/product/cws_home/600804)

The news editors report that additional information may be obtained by contacting Z.M. Lu, Jiangsu Shenhua Pharmaceut Co Ltd, Huaian 211600, Jiangsu, People's Republic of China. Additional authors for this research include Z. He, H.X. Li, J.S. Gong, Y. Geng, H.Y. Xu, G.H. Xu, J.S. Shi and Z.H. Xu.

Keywords for this news article include: Asia, Jiangsu, Biochemical Engineering, People's Republic of China

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Source: Journal of Engineering


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