Findings in Cytometry Reported from Macquarie University (On-the-fly decoding luminescence lifetimes in the microsecond region for lanthanide-encoded suspension arrays)
By a News Reporter-Staff News Editor at Science Letter -- Research findings on Cytometry are discussed in a new report. According to news originating from Sydney, Australia, by NewsRx correspondents, research stated, "Significant multiplexing capacity of optical time-domain coding has been recently demonstrated by tuning luminescence lifetimes of the upconversion nanoparticles called '?-Dots'. It provides a large dynamic range of lifetimes from microseconds to milliseconds, which allows creating large libraries of nanotags/microcarriers."
Our news journalists obtained a quote from the research from Macquarie University, "However, a robust approach is required to rapidly and accurately measure the luminescence lifetimes from the relatively slow-decaying signals. Here we show a fast algorithm suitable for the microsecond region with precision closely approaching the theoretical limit and compatible with the rapid scanning cytometry technique. We exploit this approach to further extend optical time-domain multiplexing to the downconversion luminescence, using luminescence microspheres wherein lifetimes are tuned through luminescence resonance energy transfer. We demonstrate real-time discrimination of these microspheres in the rapid scanning cytometry, and apply them to the multiplexed probing of pathogen DNA strands."
According to the news editors, the research concluded: "Our results indicate that tunable luminescence lifetimes have considerable potential in high-throughput analytical sciences."
For more information on this research see: On-the-fly decoding luminescence lifetimes in the microsecond region for lanthanide-encoded suspension arrays. Nature Communications, 2014;5():3741. (Nature Publishing Group - www.nature.com/; Nature Communications - www.nature.com/ncomms/)
The news correspondents report that additional information may be obtained from Y. Lu, Advanced Cytometry Laboratories, ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP), Macquarie University, Sydney, New South Wales 2109, Australia. Additional authors for this research include J. Lu, J. Zhao, J. Cusido, F.M. Raymo, J. Yuan, S. Yang, R.C. Leif, Y. Huo, J.A. Piper, J. Paul Robinson, E.M. Goldys and D. Jin (see also Cytometry).
Keywords for this news article include: Sydney, Cytometry, Australia and New Zealand.
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC