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Study Results from P. Terejanszky et al Provide New Insights into Silicon Dioxide (Calibration-Less Sizing and Quantitation of Polymeric...

July 1, 2014



Study Results from P. Terejanszky et al Provide New Insights into Silicon Dioxide (Calibration-Less Sizing and Quantitation of Polymeric Nanoparticles and Viruses with Quartz Nanopipets)

By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Silicon Dioxide are presented in a new report. According to news reporting out of Budapest, Hungary, by NewsRx editors, research stated, "The feasibility of using quartz nanopipets as simple and cost-effective Coulter counters for calibration-less quantitation and sizing of nanoparticles by resistive pulsing sensing (RPS) was investigated. A refined theory was implemented to calculate the size distribution of nanoparticles based on the amplitude of resistive pulses caused by their translocation through nanopipets of known geometry."

Our news journalists obtained a quote from the research, "The RPS provided diameters of monodisperse latex nanoparticles agreed within the experimental error with those measured by using scanning electron microscopy (SEM), dynamic light scattering (DLS), and nanoparticle tracking analysis (NTA). The nanopipet-based counter, by detecting individual nanoparticles, could resolve with similar resolution as SEM mixtures of monodisperse nanoparticles having partially overlapping size distributions, which could not be discriminated by DLS or NTA. Furthermore, by calculating the hydrodynamic resistance of the nanopipets and consequently the volume flow through the tip enabled for the first time the calibration-less determination of nanoparticle concentrations with nanopipets."

According to the news editors, the research concluded: "The calibration-less methodology is applied to sizing and quantitation of inactivated poliovirus of similar to 26 nm diameter, which is the smallest size spherical shape virus ever measured by resistive pulse sensing."

For more information on this research see: Calibration-Less Sizing and Quantitation of Polymeric Nanoparticles and Viruses with Quartz Nanopipets. Analytical Chemistry, 2014;86(10):4688-4697. Analytical Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Analytical Chemistry - www.pubs.acs.org/journal/ancham)

Our news journalists report that additional information may be obtained by contacting P. Terejanszky, HAS Res Center Nat Sci, MEMS Lab, H-1121 Budapest, Hungary. Additional authors for this research include I. Makra, P. Furjes and R.E. Gyurcsanyi (see also Silicon Dioxide).

Keywords for this news article include: Europe, Quartz, Hungary, Budapest, Nanoparticle, Nanotechnology, Silicon Dioxide, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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