News Column

Study Data from Tata Memorial Hospital Update Understanding of Gene Therapy (Applications of lentiviral vectors in molecular imaging)

July 3, 2014



By a News Reporter-Staff News Editor at Gene Therapy Weekly -- Current study results on Biotechnology have been published. According to news reporting originating in Navi Mumbai, India, by NewsRx journalists, research stated, "Molecular imaging provides the ability of simultaneous visual and quantitative estimation of long term gene expression directly from living organisms. To reveal the kinetics of gene expression by imaging method, often sustained expression of the transgene is required."

The news reporters obtained a quote from the research from Tata Memorial Hospital, "Lentiviral vectors have been extensively used over last fifteen years for delivery of a transgene in a wide variety of cell types. Lentiviral vectors have the well known advantages such as sustained transgene delivery through stable integration into the host genome, the capability of infecting non-dividing and dividing cells, broad tissue tropism, a reasonably large carrying capacity for delivering therapeutic and reporter gene combinations. Additionally, they do not express viral proteins during transduction, have a potentially safe integration site profile, and a relatively easy system for vector manipulation and infective viral particle production. As a result, lentiviral vector mediated therapeutic and imaging reporter gene delivery to various target organs areas holds promise for the future treatment."

According to the news reporters, the research concluded: "In this review, we have conducted a brief survey of important lentiviral vector developments in diverse biomedical fields including reproductive biology."

For more information on this research see: Applications of lentiviral vectors in molecular imaging. Frontiers in Bioscience-Landmark, 2014;19():835-853. Frontiers in Bioscience-Landmark can be contacted at: Frontiers In Bioscience Inc, 16471 Scientific Way, Irvine, CA 92618, USA (see also Biotechnology).

Our news correspondents report that additional information may be obtained by contacting S. Chatterjee, Tata Mem Hosp, ACTREC, Mol Funct Imaging Lab, Kharghar, Navi Mumbai, India.

Keywords for this news article include: Asia, Biotechnology, India, Navi Mumbai, Gene Therapy, Bioengineering, Nanotechnology, Molecular Imaging, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Gene Therapy Weekly


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