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Studies from University of California Have Provided New Data on Bacteriophages (Capture and detection of T7 bacteriophages on a nanostructured...

July 1, 2014



Studies from University of California Have Provided New Data on Bacteriophages (Capture and detection of T7 bacteriophages on a nanostructured interface)

By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Bacteriophages is the subject of a report. According to news reporting from Davis, California, by NewsRx journalists, research stated, "A highly ordered array of T7 bacteriophages was created by the electrophoretic capture of phages onto a nanostructured array with wells that accommodated the phages. Electrophoresis of bacteriophages was achieved by applying a positive potential on an indium tin oxide electrode at the bottom of the nanowells."

The news correspondents obtained a quote from the research from the University of California, "Nanoscale arrays of phages with different surface densities were obtained by changing the electric field applied to the bottom of the nanowells. The applied voltage was shown to be the critical factor in generating a well-ordered phage array. The number of wells occupied by a phage, and hence the concentration of phages in a sample solution, could be quantified by using a DNA intercalating dye that rapidly stains the T7 phage. The fluorescence signal was enhanced by the intrinsic photonic effect made available by the geometry of the platform. It was shown that the quantification of phages on the array was 6 orders of magnitude better than could be obtained with a fluorescent plate reader."

According to the news reporters, the research concluded: "The device opens up the possibility that phages can be detected directly without enrichment or culturing, and by detecting phages that specifically infect bacteria of interest, rapid pathogen detection becomes possible."

For more information on this research see: Capture and detection of T7 bacteriophages on a nanostructured interface. Acs Applied Materials & Interfaces, 2014;6(7):4758-65. (American Chemical Society - www.acs.org; Acs Applied Materials & Interfaces - www.pubs.acs.org/journal/aamick)

Our news journalists report that additional information may be obtained by contacting J.H. Han, Dept. of Mechanical and Aerospace Engineering, Food Science and Technology and Biological and Agricultural Engineering, University of California, Davis , Davis, California 95616, United States. Additional authors for this research include M.S. Wang, J. Das, L. Sudheendra, E. Vonasek, N. Nitin and I.M Kennedy (see also Bacteriophages).

Keywords for this news article include: Davis, Viruses, California, United States, Bacteriophages, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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