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Studies from Laboratory of Environmental Toxicology Have Provided New Data on Nanoparticles (Uptake, localization and clearance of quantum dots in...

July 1, 2014



Studies from Laboratory of Environmental Toxicology Have Provided New Data on Nanoparticles (Uptake, localization and clearance of quantum dots in ciliated protozoa Tetrahymena thermophila)

By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Nanoparticles have been presented. According to news reporting originating from Tallinn, Estonia, by NewsRx correspondents, research stated, "Protozoa as phagocytizing cells have been shown to integrate engineered nanoparticles (NPs), while the mechanism, dynamics and extent of such uptake are unclear. Here our fluorescence microscopy data showed that CdSe/ZnS quantum dots (QDs) with primary size of 12 nm were readily phagocytized into the food vacuoles of Tetrahymena thermophila in a time- and dose-dependent manner."

Our news editors obtained a quote from the research from the Laboratory of Environmental Toxicology, "Twenty hours after the exposure to QDs in sublethal concentration the clearance of the QDs from the cells was incomplete suggesting that phagocytosis of QDs into food vacuoles was not the only pathway of uptake by T. thermophila. This was further proven by the results that the inhibition of phagocytosis did not block the internalization of QDs into protozoans."

According to the news editors, the research concluded: "This study provides a new insight into uptake and cellular trafficking of subtoxic concentrations of nanoparticles that may, due to prolonged retention times in the cells, pose risks by potentially becoming available to higher trophic levels."

For more information on this research see: Uptake, localization and clearance of quantum dots in ciliated protozoa Tetrahymena thermophila. Environmental Pollution, 2014;190():58-64. Environmental Pollution can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Environmental Pollution - www.elsevier.com/wps/product/cws_home/405856)

The news editors report that additional information may be obtained by contacting M. Mortimer, NICPB, Lab Environm Toxicol, EE-12618 Tallinn, Estonia. Additional authors for this research include A. Kahru and V.I. Slaveykova (see also Nanoparticles).

Keywords for this news article include: Europe, Tallinn, Estonia, Quantum Dots, Nanotechnology, Quantum Physics, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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