Researchers from Chongqing University Report New Studies and Findings in the Area of Scleroproteins (Surface modification of titanium substrates with silver nanoparticles embedded sulfhydrylated chitosan/gelatin polyelectrolyte multilayer films ...)
By a News Reporter-Staff News Editor at Health & Medicine Week -- A new study on Proteins is now available. According to news reporting out of Chongqing, People's Republic of China, by NewsRx editors, research stated, "To develop Ti implants with potent antibacterial activity, a novel 'sandwich-type' structure of sulfhydrylated chitosan (Chi-SH)/gelatin (Gel) polyelectrolyte multilayer films embedding silver (Ag) nanoparticles was coated onto titanium substrate using a spin-assisted layer-by-layer assembly technique. Ag ions would be enriched in the polyelectrolyte multilayer films via the specific interactions between Ag ions and -HS groups in Chi-HS, thus leading to the formation of Ag nanoparticles in situ by photo-catalytic reaction (ultraviolet irradiation)."
Our news journalists obtained a quote from the research from Chongqing University, "Contact angle measurement and field emission scanning electron microscopy equipped with energy dispersive X-ray spectroscopy were employed to monitor the construction of Ag-containing multilayer on titanium surface, respectively. The functional multilayered films on titanium substrate [Ti/PEI/(Gel/Chi-SH/Ag) (n) /Gel] could efficiently inhibit the growth and activity of Bacillus subtitles and Escherichia coli onto titanium surface. Moreover, studies in vitro confirmed that Ti substrates coating with functional multilayer films remained the biological functions of osteoblasts, which was reflected by cell morphology, cell viability and ALP activity measurements."
According to the news editors, the research concluded: "This study provides a simple, versatile and generalized methodology to design functional titanium implants with good cyto-compatibility and antibacterial activity for potential clinical applications."
For more information on this research see: Surface modification of titanium substrates with silver nanoparticles embedded sulfhydrylated chitosan/gelatin polyelectrolyte multilayer films for antibacterial application. Journal of Materials Science-Materials in Medicine, 2014;25(6):1435-1448. Journal of Materials Science-Materials in Medicine can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands (see also Proteins).
Our news journalists report that additional information may be obtained by contacting W. Li, Chongqing Univ, Coll Commun Engn, Chongqing 400044, People's Republic of China. Additional authors for this research include D.W. Xu, Y. Hu, K.Y. Cai and Y.C. Lin.
Keywords for this news article include: Asia, Gelatin, Titanium, Chongqing, Light Metals, Nanoparticle, Nanotechnology, Scleroproteins, Emerging Technologies, People's Republic of China
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