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Reports Outline Entomology Findings from Southwest University (Highly efficient multiplex targeted mutagenesis and genomic structure variation in...

July 1, 2014



Reports Outline Entomology Findings from Southwest University (Highly efficient multiplex targeted mutagenesis and genomic structure variation in Bombyx mori cells using CRISPR/Cas9)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Life Science Research have been published. According to news reporting originating from Chongqing, People's Republic of China, by NewsRx correspondents, research stated, "Bombyx mari is an economically important insect and a model organism for studying lepidopteran and arthropod biology."

Our news editors obtained a quote from the research from Southwest University, "Using a highly efficient CRISPR/Cas9 system, we showed that this system could mediate highly efficient targeted genome editing of a single gene locus, large chromosomal deletion or inversion, and also multiplex genome editing of 6 genes simultaneously in BmNs cell line derived from B. mori."

According to the news editors, the research concluded: "The simplicity and high efficiency of our system provide unprecedented possibilities for researchers to implement precise and sophisticated manipulation of a chosen B. mori gene in BmNs cells easily in a limited time course, and perhaps new opportunities for functional genomics of B. mori and other lepidopteran insects."

For more information on this research see: Highly efficient multiplex targeted mutagenesis and genomic structure variation in Bombyx mori cells using CRISPR/Cas9. Insect Biochemistry and Molecular Biology, 2014;49():35-42. Insect Biochemistry and Molecular Biology can be contacted at: Pergamon-Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England. (Elsevier - www.elsevier.com; Insect Biochemistry and Molecular Biology - www.elsevier.com/wps/product/cws_home/390)

The news editors report that additional information may be obtained by contacting Y.Y. Liu, Southwest University, State Key Lab Silkworm Genome Biol, Chongqing 400716, People's Republic of China. Additional authors for this research include S.Y. Ma, X.G. Wang, J.S. Chang, J. Gao, R. Shi, J.D. Zhang, W. Lu, Y. Liu, P. Zhao and Q.Y. Xia (see also Life Science Research).

Keywords for this news article include: Asia, Chongqing, Life Science Research, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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