Reports on Nanoparticles Findings from Johannes Gutenberg-University Provide New Insights (Molybdenum Trioxide Nanoparticles with Intrinsic Sulfite Oxidase Activity)
Our news journalists obtained a quote from the research from Johannes Gutenberg-University, "Therefore, it plays a major role in detoxification processes, where defects in the enzyme cause a severe infant disease leading to early death with no efficient or cost-effective therapy in sight. Here we report that molybdenum trioxide (MoO3) nanoparticles display an intrinsic biomimetic sulfite oxidase activity under physiological conditions, and, functionalized with a customized bifunctional ligand containing dopamine as anchor group and triphenylphosphonium ion as targeting agent, they selectively target the mitochondria while being highly dispersible in aqueous solutions."
According to the news editors, the research concluded: "Chemically induced sulfite oxidase knockdown cells treated with MoO3 nanoparticles recovered their sulfite oxidase activity in vitro, which makes MoO3 nanoparticles a potential therapeutic for sulfite oxidase deficiency and opens new avenues for cost-effective therapies for gene-induced deficiencies."
For more information on this research see: Molybdenum Trioxide Nanoparticles with Intrinsic Sulfite Oxidase Activity. ACS
Our news journalists report that additional information may be obtained by contacting
Keywords for this news article include: Mainz,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
Most Popular Stories
- Steve Ballmer Files Six-Figure Counterclaim vs. Steve Gordon
- Creepers! Microsoft Buys 'Minecraft' Maker for $2.5 Billion
- Back to School, Even in Immigration Jail
- When to Say No to Investors, Yes to Mentors
- Hispanic Buying Power Slow but Growing in South
- Apple: Record iPhones 6 Orders on 1st Day
- U.S. Factory Output Slowed 0.4 Percent in August
- Is a Mayweather, Pacquiao Big-Money Fight Possible?
- Clinton: 'Fabulous to Be Back' in Iowa
- 'No Good Deed' Defeats 'Guardians' at Theaters