Reports from Sun Yat Sen University Provide New Insights into Bone Research [Preparation and Characterization of a Poly(methyl methacrylate) Based Composite Bone Cement Containing Poly(acrylate-co-silane) Modified Hydroxyapatite Nanoparticles]
By a News Reporter-Staff News Editor at Health & Medicine Week -- Fresh data on Bone Research are presented in a new report. According to news reporting from Guangdong, People's Republic of China, by NewsRx journalists, research stated, "The purpose of this study was to study the mechanical properties of poly(methyl methacrylate) (PMMA)-based bone cement incorporated with hydroxyapatite (HA) nanoparticles after surface modification by poly(methyl methacrylate-co--methacryloxypropyl timethoxysilane) [P(MMA-co-MPS)]. PMMA and P(MMA-co-MPS) were synthesized via free-radical polymerization."
The news correspondents obtained a quote from the research from Sun Yat Sen University, "P(MMA-co-MPS)-modified hydroxyapatite (m-HA) was prepared via a dehydration process between silane and HA; the bone cement was then prepared via the in situ free-radical polymerization of methyl methacrylate in the presence of PMMA and P(MMA-co-MPS)-m-HA. Fourier transform infrared (FTIR) spectroscopy, H-1-NMR, and gel permeation chromatography were used to characterize the P(MMA-co-MPS). Thermogravimetric analysis and FTIR were used as quantitative analysis methods to measure the content of P(MMA-co-MPS) on the surface of HA. The effect of the proportion of m-HA in the PMMA-based bone cement on the mechanical properties was studied with a universal material testing machine. A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was also carried out to determine the cytotoxicity of the composite bone cement."
According to the news reporters, the research concluded: "The results showed that the surface modification of HA greatly improved the interaction between the inorganic and organic interfaces; this enhanced the mechanical properties of bone cement for potential clinical applications."
For more information on this research see: Preparation and Characterization of a Poly(methyl methacrylate) Based Composite Bone Cement Containing Poly(acrylate-co-silane) Modified Hydroxyapatite Nanoparticles. Journal of Applied Polymer Science, 2014;131(15):655-662. Journal of Applied Polymer Science can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Journal of Applied Polymer Science - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1097-4628)
Our news journalists report that additional information may be obtained by contacting M.Y. Rao, Sun Yat Sen UniversitySch Engn, Biomed Engn Program, Guangzhou 510006, Guangdong, People's Republic of China. Additional authors for this research include Q.W. Su, Z.Z. Liu, P.Q. Liang, N. Wu, C.Y. Quan and Q. Jiang (see also Bone Research).
Keywords for this news article include: Asia, Guangdong, Phosphates, Nanoparticle, Bone Research, Methacrylates, Nanotechnology, Hydroxyapatites, Phosphoric Acids, Emerging Technologies, People's Republic of China
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