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New Corpus Luteum Hormones Study Results from M.R. Guilherme et al Described [Polycaprolactone nanoparticles containing encapsulated progesterone...

July 1, 2014



New Corpus Luteum Hormones Study Results from M.R. Guilherme et al Described [Polycaprolactone nanoparticles containing encapsulated progesterone prepared using a scCO(2) emulsion drying technique]

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Corpus Luteum Hormones have been published. According to news reporting originating from Aracaju, Brazil, by NewsRx correspondents, research stated, "Well-defined polycaprolactone (PCL) nanoparticles loaded with progesterone (P4) were obtained by scCO(2) antisolvent expansion of emulsions as a drying strategy. PCL nanoparticles with an average diameter of 82 nm were formed by the emulsification of an ethyl acetate-water mixture containing P4 and poly(vinyl alcohol) (PVA) as the stabilizing agent under ultrasonic irradiation."

Our news editors obtained a quote from the research, "Emulsion particles were dried in scCO(2) and the results were compared with drying at ambient conditions. The scCO(2) expansion-dried PCL nanoparticles showed a smaller average diameter and the dynamic light scattering (DLS) analysis revealed a narrower particle size distribution when compared to the diameter of nanoparticles formed with the conventional process (174 nm)."

According to the news editors, the research concluded: "The use of scCO(2) expansion technology as a drying strategy for the production of PCL nanoparticles with a narrow size distribution for P4 delivery represents an improvement over the conventional drying processes."

For more information on this research see: Polycaprolactone nanoparticles containing encapsulated progesterone prepared using a scCO(2) emulsion drying technique. Materials Letters, 2014;124():197-200. Materials Letters can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Materials Letters - www.elsevier.com/wps/product/cws_home/505672)

The news editors report that additional information may be obtained by contacting M.R. Guilherme, Univ Tieradentes, Inst Tecnol & Pesquisa, Center NanoMed CNanoMed, BR-49032490 Aracaju, SE, Brazil. Additional authors for this research include M.R. Mauricio, E.T. Tenorio-Neto, M.H. Kunita, L. Cardozo, T.S.P. Cellet, G.M. Pereira, E.C. Muniz, S.R.P. da Rocha and A.F. Rubira (see also Corpus Luteum Hormones).

Keywords for this news article include: Brazil, Aracaju, Nanoparticle, Progesterone, South America, Nanotechnology, Emerging Technologies, Corpus Luteum Hormones

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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