News Column

Masaryk University Details Findings in Enzymes and Coenzymes (Computational tools for designing and engineering enzymes)

July 1, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Enzymes and Coenzymes is the subject of a report. According to news reporting out of Brno, Czech Republic, by NewsRx editors, research stated, "Protein engineering strategies aimed at constructing enzymes with novel or improved activities, specificities, and stabilities greatly benefit from in ado methods. Computational methods can be principally grouped into three main categories: bioinformatics; molecular modelling; and de novo design."

Our news journalists obtained a quote from the research from Masaryk University, "Particularly de novo protein design is experiencing rapid development, resulting in more robust and reliable predictions. A recent trend in the field is to combine several computational approaches in an interactive manner and to complement them with structural analysis and directed evolution."

According to the news editors, the research concluded: "A detailed investigation of designed catalysts provides valuable information on the structural basis of molecular recognition, biochemical catalysis, and natural protein evolution."

For more information on this research see: Computational tools for designing and engineering enzymes. Current Opinion in Chemical Biology, 2014;19():8-16. Current Opinion in Chemical Biology can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier -; Current Opinion in Chemical Biology -

Our news journalists report that additional information may be obtained by contacting J. Damborsky, Masaryk University, Fac Sci, Res Center Tox Cpds Environm, Brno 62500, Czech Republic (see also Enzymes and Coenzymes).

Keywords for this news article include: Brno, Europe, Engineering, Czech Republic, Enzymes and Coenzymes

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Source: Life Science Weekly

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