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Findings from National Institutes of Health Broaden Understanding of Gene Therapy (Functional Magnetic Nanoparticles for Non-Viral Gene Delivery and...

July 3, 2014



Findings from National Institutes of Health Broaden Understanding of Gene Therapy (Functional Magnetic Nanoparticles for Non-Viral Gene Delivery and MR Imaging)

By a News Reporter-Staff News Editor at Gene Therapy Weekly -- New research on Biotechnology is the subject of a report. According to news reporting out of Bethesda, Maryland, by NewsRx editors, research stated, "Gene therapy is becoming a promising strategy to treat various kinds of genetic and acquired diseases. However, the development of safe, efficient, and targetable gene delivery systems remains a major challenge in gene therapy."

Our news journalists obtained a quote from the research from the National Institutes of Health, "The unique material characteristics of magnetic nanoparticles (MNPs), including high surface area, facile surface modification, controllable size, and excellent magnetic properties, make them promising candidates for gene delivery. The engineered MNPs with modifiable functional surfaces and bioactive cores can result in several advantageous diagnostic and therapeutic properties including enhanced magnetic resonance imaging (MRI) signal intensity, long permeation and retention in the circulatory system, specific delivery of therapeutic genes to target sites."

According to the news editors, the research concluded: "In this review, the updated research on the preparation and surface modification of MNPs for gene delivery is summarized."

For more information on this research see: Functional Magnetic Nanoparticles for Non-Viral Gene Delivery and MR Imaging. Pharmaceutical Research, 2014;31(6):1377-1389. Pharmaceutical Research can be contacted at: Springer, Plenum Publishers, 233 Spring St, New York, NY 10013, USA. (Springer - www.springer.com; Pharmaceutical Research - www.springerlink.com/content/0724-8741/)

Our news journalists report that additional information may be obtained by contacting R.J. Xing, NIBIB, Lab Mol Imaging & Nanomed LOMIN, National Institutes of Health, Bethesda, MD 20892, United States. Additional authors for this research include G. Liu, J.H. Zhu, Y.L. Hou and X.Y. Chen (see also Biotechnology).

Keywords for this news article include: Biotechnology, Bethesda, Maryland, Gene Therapy, United States, Bioengineering, Nanotechnology, Emerging Technologies, Magnetic Nanoparticles, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Gene Therapy Weekly


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