Data on Zinc Oxide Nanotechnology Detailed by Researchers at Indian Institute of Technology (Ciprofloxacin conjugated zinc oxide nanoparticle: A camouflage towards multidrug resistant bacteria)
By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Nanotechnology. According to news reporting originating from Kharagpur, India, by NewsRx correspondents, research stated, "Gradual development of antibiotic resistant bacteria is producing severe global threat. Newer strategies are now being employed in order to control the microbial infections and to reduce the mortality as well as infection rates."
Our news editors obtained a quote from the research from the Indian Institute of Technology, "Herein we describe successful synthesis of ZnO nanoparticles (ZNP) under microwave assisted condition followed by functionalization with ciprofloxacin, an antibiotic, using EDC/NHS chemistry. Successful conjugation of ciprofloxacin was confirmed by FTIR spectra. Ciprofloxacin-conjugated ZnO nanoparticles (ZN-CIP) exhibited excellent antibacterial activity against clinically isolated multidrug resistant bacterial strains of Escherichia coli, Staphylococcus aureus and Klebsiella sp. ZNP were small in size with particle size distribution 18-20 nm as obtained from transmission electronmicroscope (TEM). Surface topology was obtained from atomic force microscopic (AFM) image and x-ray diffraction confirmed that ZNP possessed hexagonal crystal structure. A concentration of 10 mu g/mL of ZN-CIP was a benchmark concentration."
According to the news editors, the research concluded: "During evaluation of minimum inhibitory concentration (MIC) values, similar concentration of antibiotic was incapable of producing antibacterial activity."
For more information on this research see: Ciprofloxacin conjugated zinc oxide nanoparticle: A camouflage towards multidrug resistant bacteria. Bulletin of Materials Science, 2014;37(2):199-206. Bulletin of Materials Science can be contacted at: Indian Acad Sciences, C V Raman Avenue, Sadashivanagar, P B #8005, Bangalore 560 080, India. (Springer - www.springer.com; Bulletin of Materials Science - www.springerlink.com/content/0250-4707/)
The news editors report that additional information may be obtained by contacting P. Patra, Indian Inst Technol, Dept. of Chem, Kharagpur 721302, W Bengal, India. Additional authors for this research include S. Mitra, N. Debnath, P. Pramanik and A. Goswami (see also Nanotechnology).
Keywords for this news article include: Asia, India, Kharagpur, Chemicals, Chemistry, Zinc Oxide, Nanoparticle, Nanotechnology, Emerging Technologies
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