News Column

Data on Pharmaceutical and Biomedical Analysis Reported by Researchers at Drexel University (Investigation of a new core-shell particle column for...

July 2, 2014



Data on Pharmaceutical and Biomedical Analysis Reported by Researchers at Drexel University (Investigation of a new core-shell particle column for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides)

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Biotechnology have been published. According to news originating from Philadelphia, Pennsylvania, by NewsRx correspondents, research stated, "A new core-shell particle column showed excellent performance and durability for separation of short (similar to 21-mer) ribonucleic acid (RNA) oligonucleotides by ion-pair reversed-phase liquid chromatography (IP-RPLC)."

Our news journalists obtained a quote from the research from Drexel University, "Previously investigated core-shell C18 columns showed excellent peak shapes and separations of closely eluting impurities by IP-RPLC. However, these columns showed only modest long-term stability at the neutral pH and elevated column temperatures of >= 60 degrees C, typically used for IP-RPLC analysis of oligonucleotides."

According to the news editors, the research concluded: "The newly introduced SunShell C18 column provided separations comparable to the previously evaluated core-shell columns, but with significantly improved long-term column stability when operated at neutral pH and elevated column temperature."

For more information on this research see: Investigation of a new core-shell particle column for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides. Journal of Pharmaceutical and Biomedical Analysis, 2014;96():54-57. Journal of Pharmaceutical and Biomedical Analysis can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Pharmaceutical and Biomedical Analysis - www.elsevier.com/wps/product/cws_home/525434)

The news correspondents report that additional information may be obtained from M. Biba, Drexel University, Dept. of Chem, Philadelphia, PA 19101, United States. Additional authors for this research include C.J. Welch and J.P. Foley (see also Biotechnology).

Keywords for this news article include: Biotechnology, Philadelphia, Pennsylvania, United States, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


For more stories covering the world of technology, please see HispanicBusiness' Tech Channel



Source: Biotech Week


Story Tools






HispanicBusiness.com Facebook Linkedin Twitter RSS Feed Email Alerts & Newsletters