News Column

Study Findings on Nanoparticles Are Outlined in Reports from L. Yang and Colleagues

June 27, 2014

By a News Reporter-Staff News Editor at Science Letter -- Research findings on Nanoparticles are discussed in a new report. According to news reporting from Richland, Washington, by NewsRx journalists, research stated, "In this study, we report new results of in situ study of 5 nm goat anti-mouse IgG gold nanoparticles in a novel portable vacuum compatible microfluidic device using scanning electron microscope (SEM) and time-of-flight secondary ion mass spectrometry (ToF-SIMS). The unique feature of the liquid flow cell is that the detection window is open to the vacuum allowing direct probing of the liquid surface."

The news correspondents obtained a quote from the research, "The flow cell is composed of a silicon nitride (SiN) membrane and polydimethylsiloxane (PDMS), and it is fully compatible with vacuum operations for surface analysis. The aperture can be drilled through the 100 nm SiN membrane using a focused ion beam. Characteristic signals of the conjugated gold nanoparticles were successfully observed through the aperture by both energy-dispersive X-ray spectroscopy (EDX) in SEM and ToF-SIMS. Comparison was also made among wet samples, dry samples, and liquid sample in the flow cell using SEM/EDX. Stronger gold signal can be observed in our novel portable device by SEM/EDX compared with the wet or dry samples, respectively. Our results indicate that analyses of the nanoparticle components are better made in their native liquid environment."

According to the news reporters, the research concluded: "This is made possible using our unique microfluidic flow cell."

For more information on this research see: In situ SEM and ToF-SIMS analysis of IgG conjugated gold nanoparticles at aqueous surfaces. Surface and Interface Analysis, 2014;46(4):224-228. Surface and Interface Analysis can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell -; Surface and Interface Analysis -

Our news journalists report that additional information may be obtained by contacting L. Yang, Cowin In Situ Sci LLC, Richland, WA 99354, United States. Additional authors for this research include Z.H. Zhu, X.Y. Yu, E. Rodek, L. Saraf, T. Thevuthasan and J.P. Cowin (see also Nanoparticles).

Keywords for this news article include: Richland, Washington, United States, Nanotechnology, Gold Nanoparticles, Emerging Technologies, North and Central America

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Source: Science Letter

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