The news correspondents obtained a quote from the research, "The flow cell is composed of a silicon nitride (SiN) membrane and polydimethylsiloxane (PDMS), and it is fully compatible with vacuum operations for surface analysis. The aperture can be drilled through the 100 nm SiN membrane using a focused ion beam. Characteristic signals of the conjugated gold nanoparticles were successfully observed through the aperture by both energy-dispersive X-ray spectroscopy (EDX) in SEM and ToF-SIMS. Comparison was also made among wet samples, dry samples, and liquid sample in the flow cell using SEM/EDX. Stronger gold signal can be observed in our novel portable device by SEM/EDX compared with the wet or dry samples, respectively. Our results indicate that analyses of the nanoparticle components are better made in their native liquid environment."
According to the news reporters, the research concluded: "This is made possible using our unique microfluidic flow cell."
For more information on this research see: In situ SEM and ToF-SIMS analysis of IgG conjugated gold nanoparticles at aqueous surfaces. Surface and Interface Analysis, 2014;46(4):224-228. Surface and Interface Analysis can be contacted at: Wiley-Blackwell,
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