News Column

Study Data from University of Strathclyde Update Understanding of Chromatography

June 27, 2014



By a News Reporter-Staff News Editor at Science Letter -- Research findings on Science are discussed in a new report. According to news originating from Glasgow, United Kingdom, by NewsRx correspondents, research stated, "This paper presents eight distinct strong cation-exchange resins, all of which were derived from precursor resins that had been synthesised using either precipitation polymerisation or non-aqueous dispersion polymerisation. The precursor resins were transformed into the corresponding strong cation-exchange resins by hypercrosslinking followed by polymer analogous reactions, to yield materials with high specific surface areas and strong cation-exchange character."

Our news journalists obtained a quote from the research from the University of Strathclyde, "These novel resins were then evaluated as strong cation-exchange (SCX) sorbents in the solid-phase extraction (SPE) of a group of drugs from aqueous samples. Following preliminary experiments, the two best-performing resins were then evaluated in solid-phase extraction-liquid chromatography-tandem mass spectrometry (SPE/LC-MS/MS) to determine a group of drugs from sewage samples. In general, use of these sorbents led to excellent recovery values (75-100%) for most of the target drugs and negligible matrix effects (ME) (

According to the news editors, the research concluded: "Finally, a validated method based on SPE/LC-MS/MS was used to quantify the target drugs present in different sewage samples."

For more information on this research see: Evaluation of strong cation-exchange polymers for the determination of drugs by solid-phase extraction-liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 2014;1343():55-62. Journal of Chromatography A can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Chromatography A - www.elsevier.com/wps/product/cws_home/502688)

The news correspondents report that additional information may be obtained from N. Fontanals, University of Strathclyde, Dept. of Pure & Appl Chem, WestCHEM, Glasgow G1 1XL, Lanark, United Kingdom. Additional authors for this research include N. Miralles, N. Abdullah, A. Davies, N. Gilart and P.A.G. Cormack (see also Science).

Keywords for this news article include: Europe, Glasgow, Science, United Kingdom

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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